CAS 108549-23-1

Dibenzyl diisopropylphosphoramidite

Description:

Dibenzyl diisopropylphosphoramidite is a chemical compound characterized by its phosphoramidite functional group, which is commonly used in organic synthesis, particularly in the field of oligonucleotide chemistry. This compound features two benzyl groups and two isopropyl groups attached to a phosphorus atom, contributing to its steric bulk and influencing its reactivity. It is typically a colorless to pale yellow liquid at room temperature and is known for its ability to act as a protecting group for hydroxyl functionalities in nucleosides and nucleotides. The presence of the phosphoramidite moiety allows for the formation of phosphodiester bonds, making it a crucial reagent in the synthesis of DNA and RNA sequences. Additionally, dibenzyl diisopropylphosphoramidite is sensitive to moisture and air, necessitating careful handling and storage under inert conditions. Its applications extend beyond nucleic acid synthesis to include potential uses in various organic transformations and as a building block in the development of phosphorous-containing compounds.

Formula: C₂₀H₂₈NO₂P

InChI: InChI=1/C20H28NO2P/c1-17(2)21(18(3)4)24(22-15-19-11-7-5-8-12-19)23-16-20-13-9-6-10-14-20/h5-14,17-18H,15-16H2,1-4H3

InChI key: ANPWLBTUUNFQIO-UHFFFAOYSA-N

SMILES: CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1

Synonyms:

• Bis(benzyloxy)(diisopropylamino)phosphine
• Bis-bzl-2iPr-P
• Phosphoramidous acid, bis(1-methylethyl)-, bis(phenylmethyl) ester
• Dibenzyl Dipropan-2-Ylphosphoramidoite
• Dibenzyl N,N-diisopropylphosphoramidite

Dibenzyl N,N-Diisopropylphosphoramidite

CAS: 108549-23-1

Formula: C₂₀H₂₈NO₂P

Purity: >98.0%(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 345.42

Ref: 3B-D2624

Dibenzyl diisopropylphosphoramidite, 90+%

CAS: 108549-23-1

Dibenzyl N,N-diisopropylphosphoramidite may be used for the preparation of phosphopeptides. It is used for the synthesis of a GDP (guanosine diphosphate) analog, SML-8-73-1. It is useful for nucleotide coupling. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar pro

Formula: C₂₀H₂₈NO₂P

Purity: 90+%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 345.42

Ref: 02-B22629

Dibenzyl N,N-diisopropylphosphoramidite

CAS: 108549-23-1

Formula: C₂₀H₂₈NO₂P

Purity: 98%

Color and Shape: Liquid

Molecular weight: 345.4156

Ref: IN-DA0034PA

Dibenzyl N,N-diisopropylphosphoramidite

CAS: 108549-23-1

Dibenzyl N,N-diisopropylphosphoramidite

Formula: C₂₀H₂₈NO₂P

Purity: 98%

Color and Shape: Liquid

Molecular weight: 345.41558

Ref: 54-OR60102

Dibenzyldiisopropylphosphoramidite

CAS: 108549-23-1

Formula: C₂₀H₂₈NO₂P

Purity: ≥ 94.0%

Color and Shape: Colourless to light yellow liquid

Molecular weight: 345.43

Ref: 7W-GK8636

Dibenzyl N,N-diisopropylphosphoramidite

CAS: 108549-23-1

Dibenzyl diisopropylphosphoramidite

Formula: C₂₀H₂₈NO₂P

Purity: 95%

Molecular weight: 345.42

Ref: IN-DG41159

Dibenzyl N,N-diisopropylphosphoramidite

CAS: 108549-23-1

Dibenzyl N,N-diisopropylphosphoramidite is a chemical compound that has antioxidative properties. It is used in the synthesis of triazole antifungal agents and other chemical compounds. Dibenzyl N,N-diisopropylphosphoramidite has been shown to have physiological function in fatty acid metabolism. This compound also reacts with 3-chloroperoxybenzoic acid, chloride, diphenyl sulfoxide, sodium salts, hydroxy group, and silver trifluoromethanesulfonate to form an intermolecular hydrogen bond. Dibenzyl N,N-diisopropylphosphoramidite can react with transfer reactions to form a variety of different compounds.

Formula: C₂₀H₂₈NO₂P

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 345.42 g/mol

Ref: 3D-FD02678

Dibenzyl diisopropylphosphoramidite

CAS: 108549-23-1

Formula: C₂₀H₂₈NO₂P

Purity: 95%

Color and Shape: Liquid

Molecular weight: 345.423

Ref: 10-F450233

Dibenzyl N,N-Diisopropylphosphoramidite

Controlled Product

CAS: 108549-23-1

Applications A versatile phosphitylating agent.
References Perich, J.W., et al.: Synthesis, 142 (1988)

Formula: C₂₀H₂₈NO₂P

Color and Shape: Neat

Molecular weight: 345.42

Ref: TR-D417500