CAS 108929-04-0

Epinastine hydrochloride

Description:

Epinastine hydrochloride is an antihistamine primarily used in the treatment of allergic conjunctivitis and other allergic conditions. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a compound involved in allergic responses. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in eye drops for topical administration. Epinastine hydrochloride exhibits a relatively low molecular weight and has a specific chemical structure that contributes to its pharmacological properties. Its mechanism of action not only alleviates symptoms such as itching and redness but also has anti-inflammatory effects. The compound is generally well-tolerated, with a low incidence of side effects, making it a preferred choice for managing allergic reactions. As with any medication, it is important to follow dosing guidelines and consult healthcare professionals for appropriate use.

Formula: C₁₆H₁₅N₃·ClH

InChI: InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChI key: InChIKey=VKXSGUIOOQPGAF-UHFFFAOYSA-N

SMILES: NC=1N2C(C=3C(CC=4C2=CC=CC4)=CC=CC3)CN1.Cl

Synonyms:

• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1)
• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, monohydrochloride
• 3-Amino-9,13b-Dihydro-1h-Dibenz[C,F]Imidazo[1,5-A]Azepine Hydrochloride
• 9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (1:1)
• Alesion
• Elestat
• Epinastin Hcl
• Epinastine hcl
• Wal 801Cl
• Epinastine hydrochloride
• Epinastine Hydrochloride

Epinastine Hydrochloride

CAS: 108929-04-0

Formula: C₁₆H₁₅N₃·HCl

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 285.78

Ref: 3B-E0799

EPINASTINE HYDROCHLORIDE CRS

CAS: 108929-04-0

EPINASTINE HYDROCHLORIDE CRS

Formula: C₁₆H₁₆ClN₃

Color and Shape: Crystalline Powder. White. Whitish. Powder.

Molecular weight: 285.7713

Ref: 41-Y0001139

EPINASTINE FOR SYSTEM SUITABILITY A CRS

CAS: 108929-04-0

EPINASTINE FOR SYSTEM SUITABILITY A CRS

Ref: 41-Y0002208

Epinastine Hydrochloride

CAS: 108929-04-0

Antihistamines

Formula: C₁₆H₁₅N₃·HCl

Color and Shape: White Powder

Molecular weight: 285.10328

Ref: 45-1236889

Epinastine hydrochloride

CAS: 108929-04-0

Formula: C₁₆H₁₆ClN₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 285.7713

Ref: IN-DA003PXM

Epinastine Hydrochloride

CAS: 108929-04-0

Epinastine Hydrochloride

Formula: C₁₆H₁₅N₃·HCl

Purity: >99%

Molecular weight: 285.77

Ref: 54-OR1023598

Epinastine HCl

CAS: 108929-04-0

Formula: C₁₆H₁₅N₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 249.32 36.46

Ref: 4Z-E-431

Epinastine hydrochloride

CAS: 108929-04-0

Formula: C₁₆H₁₅N₃·HCl

Molecular weight: 285.77

Ref: 7W-GP8150

Epinastine hydrochloride

CAS: 108929-04-0

Epinastine hydrochloride

Formula: C₁₆H₁₅N₃·HCl

Purity: ≥98%

Molecular weight: 285.77

Ref: 54-BUP15660

Epinastine Hydrochloride

Controlled Product

CAS: 108929-04-0

Formula: C₁₆H₁₅N₃·ClH

Color and Shape: Neat

Molecular weight: 285.77

Ref: 86-MM3383.00

Epinastine Hydrochloride

Controlled Product

CAS: 108929-04-0

Applications A tetracyclic, non-sedating histamine H1 receptor antagonist. Antihistaminic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Walther, G., et al.: Arzneim.-Forsch., 40, 440 (1990), Ohshima, E., et al.: J. Med. Chem., 35, 2074 (1992), Morita, E., et al.: J. Dermatol. 32, 58 (2005), Suzuki, G., et al.: J. Pharmacol. Exp. Ther., 321, 1144 ( 2007),

Formula: C₁₆H₁₅N₃·ClH

Color and Shape: Neat

Molecular weight: 285.77

Ref: TR-E588560

Epinastine hydrochloride

CAS: 108929-04-0

Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.

Formula: C₁₆H₁₅N₃·HCl

Purity: 99.26% - 99.62%

Color and Shape: Solid

Molecular weight: 285.77

Ref: TM-T6488

Epinastine HCl

CAS: 108929-04-0

Epinastine HCl is a drug that belongs to the class of histamine H1 receptor antagonists. It is used in the treatment of allergic symptoms such as hay fever and chronic cough. Epinastine binds to DNA, which prevents the binding of benzalkonium chloride, thereby inhibiting its adsorbing activity. This mechanism may be responsible for its anti-allergic effects. Epinastine also has bronchoconstrictor properties, which may be due to its ability to inhibit neurokinin-1 receptor and eosinophil cationic protein release from human blood cells in vitro.

Formula: C₁₆H₁₆N₃Cl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 285.77 g/mol

Ref: 3D-FE31358

Epinastine HCl - Bio-X ™

CAS: 108929-04-0

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₆H₁₆N₃Cl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 285.77 g/mol

Ref: 3D-BE300075

Epinastine Hydrochloride

CAS: 108929-04-0

Formula: C₁₆H₁₆ClN₃

Molecular weight: 285.77

Ref: BE-BePure-24292

Epinastine hydrochloride

CAS: 108929-04-0

Formula: C₁₆H₁₆ClN₃

Molecular weight: 285.77

Ref: BE-RMCE088001

Epinastine HCl

CAS: 108929-04-0

9,13B-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride

Formula: C₁₆H₁₆ClN₃

Purity: 99%

Molecular weight: 285.77

Ref: IN-DG127372

13b-Hydroxy-1-one Epinastine

Controlled Product

CAS: 108929-04-0

Formula: C₁₆H₁₃N₃O₂

Color and Shape: Neat

Molecular weight: 279.293

Ref: TR-E588370

Epinastine HCl

CAS: 108929-04-0

Formula: C₁₆H₁₅N₃HCl

Molecular weight: 249.3 : 36.46

Ref: ST-EA-CP-E25003