CAS 109028-10-6

Pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (2Z)-2-butenedioate (1:2)

Description:

Pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (2Z)-2-butenedioate (1:2), identified by CAS number 109028-10-6, is a complex organic compound characterized by its unique structural features, including a pyrroloquinoxaline core and functional groups such as a piperazine moiety and trifluoromethyl group. This compound exhibits potential biological activity, making it of interest in medicinal chemistry and pharmacology. The presence of the trifluoromethyl group often enhances lipophilicity and metabolic stability, while the piperazine ring can contribute to receptor binding and activity. The (2Z)-2-butenedioate component suggests the presence of a conjugated system, which may influence the compound's electronic properties and reactivity. Overall, this substance is likely to be investigated for its pharmacological properties, including potential applications in treating various diseases, although specific biological activities would require further empirical studies to elucidate its mechanisms of action and therapeutic potential.

Formula: C₁₇H₁₇F₃N₄·2C₄H₄O₄

InChI: InChI=1S/C17H17F3N4.C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key: InChIKey=ZBPAHEUAJMCLRD-BTJKTKAUSA-N

SMILES: CN1CCN(C=2C=3N(C=4C(N2)=CC(C(F)(F)F)=CC4)C=CC3)CC1.C(=C\C(O)=O)\C(O)=O

Synonyms:

• 4-(4-Methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline (2Z)-but-2-enedioate (1:1)
• Cgs 12066B
• Pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (2Z)-2-butenedioate (1:2)
• Pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (Z)-2-butenedioate (1:2)
• pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (2Z)-2-butenedioate (1:1)

CGS 12066B dimaleate, 98+%

CAS: 109028-10-6

5-HT-1B full agonist

Formula: C₁₇H₁₇F₃N₄·2(C₄H₄O₄)

Purity: 98+%

Molecular weight: 566.49

Ref: 02-J63801

CGS 12066B dimaleate

CAS: 109028-10-6

CGS 12066B dimaleate is a 5-HT receptor agonist that is used to study the role of serotonin in the regulation of blood pressure. It has been shown to decrease blood pressure and heart rate in vivo models. CGS 12066B dimaleate binds to both 5-HT1 and 5-HT2 receptors, but with low potency. A whole-cell recording experiment showed that this drug inhibits ATP-sensitive potassium channels, which may be responsible for its pressor activity. This drug also has a stimulant effect on locomotor activity and dopamine release, which may be due to its binding to postsynaptic dopamine receptors.

Formula: C₁₇H₁₇F₃N₄·2C₄H₄O₄

Purity: Min. 95%

Molecular weight: 566.49 g/mol

Ref: 3D-JEA02810

CGS 12066B dimaleate

CAS: 109028-10-6

5-HT1B full agonist

Formula: C₂₅H₂₅F₃N₄O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 566.48

Ref: TM-T22653