CAS 1093222-27-5

N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide

Description:

N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide, with the CAS number 1093222-27-5, is a chemical compound characterized by its complex structure, which includes a pyrrolo[2,3-b]pyridine core and a pyridinecarboxamide moiety. This compound features a cyanophenyl group, contributing to its potential electronic and steric properties. It is typically classified as an organic heterocyclic compound due to the presence of nitrogen atoms in its ring structures. The presence of multiple aromatic rings suggests that it may exhibit significant π-π stacking interactions, which can influence its solubility and reactivity. Additionally, the functional groups present may impart specific biological activities, making it of interest in medicinal chemistry and drug development. Its synthesis and characterization would involve standard organic chemistry techniques, and its properties could be further explored through various analytical methods such as NMR, mass spectrometry, and X-ray crystallography. Overall, this compound represents a class of molecules that may have applications in pharmaceuticals or materials science.

Formula: C₂₀H₁₃N₅O

InChI: InChI=1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)

InChI key: JTSLALYXYSRPGW-UHFFFAOYSA-N

SMILES: C1=CC(=CN=C1)C(=O)NC2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C#N

Synonyms:

• LKB1(AAK1 dual inhibitor)
• Pim1/AKK1-IN-1
• CS-2864
• Pim1/AKK1 inhibitor 1
• N-[5-(4-cyanophenyl)-1H-pyrrolo[2
• LKB1/AAK1 DUAL INHIBITOR;3-PYRIDINECARBOXAMIDE; N-[5-(4-CYANOPHENYL)-1H-PYRROLO[2;3-B]PYRIDIN-3-YL]-
• 3-b]pyridin-3-yl]-
• AAK1 dual inhibitor
• LKB1/AAK1 DUAL INHIBITOR;AAK1 DUAL INHIBITOR
• MDK-2275
• 3-PyridinecarboxaMide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-

Pim1/AKK1-IN-1

CAS: 1093222-27-5

Pim1/AKK1-IN-1

Formula: C₂₀H₁₃N₅O

Purity: 98.5%

Molecular weight: 339.35

Ref: 54-BUP04183

N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide

CAS: 1093222-27-5

Formula: C₂₀H₁₃N₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.3501

Ref: IN-DA008THD

Pim1/AKK1-IN-1

CAS: 1093222-27-5

Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.

Formula: C₂₀H₁₃N₅O

Purity: 97.03% - 98.69%

Color and Shape: White Solid

Molecular weight: 339.3501

Ref: TM-T5093

N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide

CAS: 1093222-27-5

N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide

Formula: C₂₀H₁₃N₅O

Purity: 98%

Molecular weight: 339.35

Ref: IN-DG629891

Pim1/AKK1-IN-1

CAS: 1093222-27-5

Pim1/AKK1-IN-1 is a new anticancer drug that is currently in clinical trials. It has been shown to be effective against breast cancer and prostate cancer cells, as well as cells from other types of cancers such as leukemia and lymphoma. This compound induces cell death by binding to DNA and inhibiting the synthesis of proteins needed for cell division. Pim1/AKK1-IN-1 also inhibits estrogen synthesis, which may explain its effectiveness against cancer cells that are dependent on estrogen for survival. There is no information available about the mechanism of action of this drug in women.

Formula: C₂₀H₁₃N₅O

Purity: Min. 95%

Molecular weight: 339.35 g/mol

Ref: 3D-TTB22227