CAS 1094-61-7

beta-nicotinamide mononucleotide

Description:

Beta-nicotinamide mononucleotide (NMN) is a nucleotide derived from ribose, nicotinamide, and phosphate. It plays a crucial role in cellular metabolism as a precursor to nicotinamide adenine dinucleotide (NAD+), a vital coenzyme involved in redox reactions and energy production within cells. NMN is recognized for its potential health benefits, particularly in aging research, as it may help enhance NAD+ levels, which tend to decline with age. This compound is typically found in small amounts in various foods, including vegetables and fruits. NMN is water-soluble, allowing for easy absorption in biological systems. Its stability can be influenced by factors such as pH and temperature, which are important considerations in storage and formulation. Research into NMN has expanded, focusing on its implications for metabolic health, neuroprotection, and overall longevity. However, while promising, further studies are necessary to fully understand its mechanisms and therapeutic potential.

Formula: C₁₁H₁₅N₂O₈P

InChI: InChI=1/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1

InChI key: InChIKey=DAYLJWODMCOQEW-TURQNECASA-N

SMILES: O[C@H]1[C@@H](O[C@H](COP(=O)([O-])O)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2

Synonyms:

• 3-(Aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium
• 3-Carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• 3-carbamoyl-1-(5-O-phosphonopentofuranosyl)pyridinium
• 3-carbamoyl-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridinium
• NMN
• NMN (mononucleotide)
• Nicotinamide mononucleotide
• Nicotinamide ribonucleoside 5′-phosphate
• Nicotinamide ribonucleotide
• Nicotinamide ribotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, hydroxide, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, inner salt
• Pyridinium, 3-carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• coenzyme NMN
• β-<span class="text-smallcaps">D</span>-NMN
• β-NMN
• β-Nicotinamide mononucleotide
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt
• Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, hydroxide, inner salt
• 3-Carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide, 5′-phosphate, inner salt
• Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5′-(dihydrogen phosphate), inner salt
• β-Nicotinamide ononucleotide
• beta-D-NMN
• Nicotinamide nucleotide
• β-nicotinamide D-ribonucleotide
• NMN zwitterion
• β-Nicotinamide Moonucleotide
• Nicotimide mononucleotide
• 99% NMN CAS 1094 61 7
• β-Nicotinamide Mononucleotid
• Nicotinamide mononuclotide
• β-Nicotinamidse Mononucleotide
• β-D-NMN
• beta-Nicotinamide Moonucleotide
• NMN powder
• BETA-NMN POWDER

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: 97%

Color and Shape: Solid

Molecular weight: 334.2192

Ref: IN-DA003880

β-Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: ≥ 95.0%

Color and Shape: White, off-white or pale yellow powder

Molecular weight: 334.22

Ref: 7W-GE9996

β-Nicotinamide Mononucleotide-13C6

CAS: 1094-61-7

Formula: C₅₁₃C₆H₁₅N₂O₈P

Molecular weight: 340.17

Ref: 4Z-N-133013

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-Nicotinamide mononucleotide

Purity: ≥98%

Molecular weight: 334.22g/mol

Ref: 54-BUP15443

β-Nicotinamide Mononucleotide Sodium Salt

CAS: 1094-61-7

Formula: C₁₁H₁₄N₂O₈P·Na

Molecular weight: 333.21 22.99

Ref: 4Z-N-133014

Nicotinamide mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: 95%~99%

Molecular weight: 334.221

Ref: BP-BP4241

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 334.22

Ref: 3B-N1123

β-Nicotinamide mononucleotide

CAS: 1094-61-7

β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). Cost effective and quality assured.

Formula: C₁₁H₁₅N₂O₈P

Purity: 99.29% - >99.99%

Color and Shape: Solid

Molecular weight: 334.22

Ref: TM-T4721

β-Nicotinamide Mononucleotide-d4

CAS: 1094-61-7

Formula: C₁₁H₁₁D₄N₂O₈P

Molecular weight: 338.25

Ref: 4Z-N-133006

β-Nicotinamide Mononucleotide-13C5

CAS: 1094-61-7

Formula: C₆₁₃C₅H₁₅N₂O₈P

Molecular weight: 339.18

Ref: 4Z-N-133007

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide

Formula: C₁₁H₁₅N₂O₈P

Purity: By hplc: 99.5% by area (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 334.21916g/mol

Ref: 54-BIB3016

β-Nicotinamide Mononucleotide

CAS: 1094-61-7

Stability Very Hygroscopic
Applications A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Formula: C₁₁H₁₅N₂O₈P

Color and Shape: White

Molecular weight: 334.22

Ref: TR-N407765

β-Nicotinamide-d4 Mononucleotide (d4-major)

Controlled Product

CAS: 1094-61-7

Formula: C₁₁D₄H₁₁N₂O₈P

Color and Shape: White To Off-White

Molecular weight: 338.244

Ref: TR-N407768

b-Nicotinamide mononucleotide

CAS: 1094-61-7

b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.

Formula: C₁₁H₁₅N₂O₈P

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 334.22 g/mol

Ref: 3D-NN45555

ß-Nicotinamide Mononucleotide (ß-NMN) extrapure, 98%

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: min. 98.0%

Color and Shape: White, Crystalline powder

Molecular weight: 334.22

Ref: SR-95130

ß-Nicotinamide Mononucleotide (ß-NMN) for cell culture, 99%, Endotoxin (BET) 0.05EU/mg

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: min. 99.0%

Color and Shape: White, Crystalline powder.

Molecular weight: 334.22

Ref: SR-63509

((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate

CAS: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Purity: 95%

Color and Shape: Solid

Molecular weight: 334.221

Ref: 10-F455506

β-Nicotinamide Mononucleotide-13C5

Controlled Product

CAS: 1094-61-7

Applications The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
References Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);

Formula: C₅C₆H₁₅N₂O₈P

Color and Shape: Neat

Molecular weight: 339.182

Ref: TR-N407767