CAS 1094048-77-7

Formula: C17H12INO5

InChI: InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+

InChI key: HSRMHXWCTRFVHK-NYYWCZLTSA-N

SMILES: COC1=C(C(=CC(=C1)/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)I)O

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

I-OMe-Tyrphostin AG 538

Formula: C₁₇H₁₂INO₅

Purity: 98.5%

Molecular weight: 437.19

Ref: 54-BUP09174

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

Formula: C₁₇H₁₂INO₅

Molecular weight: 437.1853

Ref: IN-DA024X6A

TYRPHOSTIN I-OME-AG 538

CAS: 1094048-77-7

2-(3,4-Dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile is a high purity ion channel inhibitor with IC50 of 1.8 nM. It has been shown to inhibit the activity of voltage gated sodium channels in rat hippocampal neurons and human erythrocytes. The binding affinity of 2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5 methoxyphenyl)prop-2 enenitrile for the nicotinic acetylcholine receptor (nAChR), as determined by competitive radioligand binding assay, is 21 pM. This compound also inhibits the activity of potassium channels and has been shown to bind to peptides and antibodies.

Formula: C₁₇H₁₂INO₅

Purity: Min. 95%

Molecular weight: 437.18 g/mol

Ref: 3D-UTB04877

I-OMe-Tyrphostin AG 538

CAS: 1094048-77-7

I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.

Formula: C₁₇H₁₂INO₅

Purity: 98.8%

Color and Shape: Solid

Molecular weight: 437.1854

Ref: TM-T11593