CAS 1094566-37-6

Amino Hydroxynimesulide NAC Adduct

Controlled Product

CAS: 1094566-37-6

Applications Amino Hydroxynimesulide is an analog of Nimesulide (N477500), an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998); Li, F. et al.: Chem. Res. Toxicol., 22, 72 (2009);

Formula: C₁₈H₂₁N₃O₇S₂

Color and Shape: Neat

Molecular weight: 455.51

Ref: TR-A618310