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CAS 1094617-45-4

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Fmoc-Arg(Z)2-OH

Description:
Fmoc-Arg(Z)2-OH, also known as Fmoc-dihydroxyarginine, is a protected amino acid derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The "Arg" denotes the presence of arginine, an amino acid characterized by its basic side chain, which contains a guanidinium group, contributing to its positive charge at physiological pH. The "(Z)" indicates that the side chain of arginine is protected, typically by a benzyloxycarbonyl (Z) group, which prevents unwanted reactions during synthesis. This compound is soluble in organic solvents and exhibits stability under standard laboratory conditions. Its use is prevalent in solid-phase peptide synthesis, where the protection and deprotection strategies are crucial for the successful assembly of complex peptides. Overall, Fmoc-Arg(Z)2-OH is an important building block in the field of medicinal chemistry and peptide research, facilitating the development of bioactive peptides and therapeutic agents.
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