CAS 109838-85-9

(R)-2,5-dihydro-3,6-dimethoxy-2-iso-propylpyrazine

Description:

(R)-2,5-dihydro-3,6-dimethoxy-2-iso-propylpyrazine is a chemical compound characterized by its unique pyrazine ring structure, which contributes to its aromatic properties. This compound features two methoxy groups (-OCH3) at the 3 and 6 positions, enhancing its solubility and reactivity. The presence of an isopropyl group at the 2 position adds to its steric bulk, influencing its interactions and potential applications. As a chiral molecule, it exists in two enantiomeric forms, with the (R) configuration being of particular interest in various fields, including flavor and fragrance chemistry, due to its distinctive sensory attributes. The compound is typically synthesized through specific organic reactions that allow for the selective introduction of functional groups. Its applications may extend to the food industry, where it can be utilized as a flavoring agent, as well as in the development of fragrances. Overall, (R)-2,5-dihydro-3,6-dimethoxy-2-iso-propylpyrazine is notable for its structural features and potential utility in various chemical applications.

Formula: C₉H₁₆N₂O₂

InChI: InChI=1/C9H16N2O2/c1-6(2)8-9(13-4)10-5-7(11-8)12-3/h6,8H,5H2,1-4H3/t8-/m1/s1

SMILES: CC(C)[C@@H]1C(=NCC(=N1)OC)OC

Synonyms:

• (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine
• (2R)-3,6-dimethoxy-2-(propan-2-yl)-2,5-dihydropyrazine
• (2R)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine
• 2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE
• (2R)-2,5-Dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazine
• BISLACTIMETHER
• (2R)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPYRAZINE, 98+%
• (2R)-3,6-DIMETHOXY-2-(1-METHYLETHYL)-2,5-DIHYDROPYRAZINE
• (R)-2,5-DIMETHOXY-3-ISOPROPYL-3,6-DIHYDROPYRAZINE
• zR{-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• SCHOELLKOPF-HARTWIG-REAGENT
• (2R)-(-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine (aka (R )-Schollkopf reagent)
• (R)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYLPIPERAZINE
• (-)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• (R)-Schollkopf Reagent
• Pyrazine, 2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)-, (2R)-(9CI)

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine, 98%

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazineChiral auxiliary for the synthesis of -amino acids. It is an inhibitor with antitumor activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Formula: C₉H₁₆N₂O₂

Purity: 98%

Color and Shape: Colorless to yellow to orang, Liquid

Molecular weight: 184.24

Ref: 02-H56077

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

Formula: C₉H₁₆N₂O₂

Purity: 96%

Color and Shape: Liquid

Molecular weight: 184.2355

Ref: IN-DA0032ER

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

CAS: 109838-85-9

(R)-3-Isopropyl-2,5-dimethoxy-3,6-dihydropyrazine

Formula: C₉H₁₆N₂O₂

Purity: 99%

Color and Shape: colourless to light yellow liquid

Molecular weight: 184.24g/mol

Ref: 54-OR925455

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Formula: C₉H₁₆N₂O₂

Purity: >95.0%(GC)

Color and Shape: Colorless to Yellow clear liquid

Molecular weight: 184.24

Ref: 3B-D3256

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine

CAS: 109838-85-9

Purity: 98%

Molecular weight: 184.238998413086

Ref: 10-F790908

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine

CAS: 109838-85-9

(R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine and its enantiomer (S)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine are also known as Schöllkopf chiral auxiliaries or Schöllkopf reagents, and are used to produce optically pure α-amino acids via asymmetric synthesis. The Schöllkopf reagent can be deprotonated at the prochiral α-carbon, and the resulting enolate is trapped with electrophiles to yield adducts with high (typically > 95% d.e.) diastereoselectivity. The enolate is essentially planar, and the steric bulk of the isopropyl group directs the incoming electrophile to attack from the opposite face, yielding trans adducts. A wide range of electrophiles including alkyl halides, alkyl sulfonates, acyl chlorides, aldehydes, ketones, epoxides, thioketones and enones can be used. Hydrolysis, typically under mild acidic conditions, yields the non-substituted amino acid with high (typically > 95 e.e.) enantiopurity.

Formula: C₉H₁₆N₂O₂

Purity: Min. 98%

Color and Shape: Colorless Yellow Clear Liquid

Molecular weight: 184.24 g/mol

Ref: 3D-FD04039

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine (>85% Purity)

Controlled Product

CAS: 109838-85-9

Stability Moisture Sensitive
Applications An inhibitor with antitumor activity.
References Plumb, J., et al.: Mol. Cancer Ther., 2, 721 (2003), de Ruijter, A., et al.: Biochem. J., 370, 737 (2003), Dey, P., et al.: Curr. Med. Chem., 13, 2909 (2006), Maiso, P., et al.: Cancer Res., 66, 5781 (2006), Paris, M., et al.: J. Med. Chem., 51, 1505 (2008),

Formula: C₉H₁₆N₂O₂

Purity: >85%

Color and Shape: Neat

Molecular weight: 184.24

Ref: TR-I824430