CAS 1103500-20-4

Formula: C28H27Cl2N3O4

InChI: InChI=1S/C28H27Cl2N3O4/c1-32-14-20(28(34)35)19-8-7-17(13-24(19)32)33-11-9-18(10-12-33)36-15-21-26(31-37-27(21)16-5-6-16)25-22(29)3-2-4-23(25)30/h2-4,7-8,13-14,16,18H,5-6,9-12,15H2,1H3,(H,34,35)

InChI key: RPVDFHPBGBMWID-UHFFFAOYSA-N

SMILES: CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O

LY2562175

CAS: 1103500-20-4

LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).

Formula: C₂₈H₂₇Cl₂N₃O₄

Purity: 99.16% - 99.63%

Color and Shape: Solid

Molecular weight: 540.438

Ref: TM-T15806

LY2562175

CAS: 1103500-20-4

LY2562175

Formula: C₂₈H₂₇Cl₂N₃O₄

Purity: ≥98%

Molecular weight: 540.44

Ref: 54-BUP08649

LY2562175

CAS: 1103500-20-4

Formula: C₂₈H₂₇Cl₂N₃O₄

Purity: 99%

Molecular weight: 540.4377

Ref: IN-DA01EOFV

LY2562175

CAS: 1103500-20-4

6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid

Formula: C₂₈H₂₇Cl₂N₃O₄

Purity: 99%

Molecular weight: 540.44

Ref: IN-DG01071364

LY2562175

Controlled Product

CAS: 1103500-20-4

Formula: C₂₈H₂₇Cl₂N₃O₄

Color and Shape: Neat

Molecular weight: 540.438

Ref: TR-L490015

LY2562175

Controlled Product

CAS: 1103500-20-4

LY2562175 is a small molecule that inhibits diacylglycerol (DAG) production. It binds to the enzyme DAG kinase, which is responsible for catalyzing the phosphorylation of DAG to form phosphatidic acid. LY2562175 has been shown to reduce lipid levels in humans and improve dyslipidemia. LY2562175 also has inhibitory activity against primary sclerosing cholangitis, a chronic inflammatory condition of the bile ducts in the liver. The mechanism of action for this drug is not fully understood but it may be due to its ability to inhibit cell proliferation and the production of pro-inflammatory cytokines by immune cells. LY2562175 has undergone clinical trials as a diagnostic tool for primary sclerosing cholangitis and safety profiles have been evaluated in pharmacokinetic studies.

Formula: C₂₈H₂₇Cl₂N₃O₄

Purity: Min. 95%

Molecular weight: 540.44 g/mol

Ref: 3D-DUB50020