CAS 110764-78-8

Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Description:

Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a complex nucleoside derivative primarily used in the field of molecular biology and biochemistry, particularly in the synthesis of oligonucleotides. This compound features a cytidine base, which is a nucleoside composed of a pyrimidine base (cytosine) and a ribose sugar, modified with various functional groups that enhance its stability and reactivity. The presence of the N-benzoyl group and the bis(4-methoxyphenyl)phenylmethyl moiety contributes to its lipophilicity and solubility in organic solvents, making it suitable for various synthetic applications. The 2′-O-methyl modification provides resistance to enzymatic degradation, while the phosphoramidite group allows for efficient coupling during oligonucleotide synthesis. Overall, this compound is characterized by its structural complexity, functional versatility, and utility in the development of nucleic acid-based technologies.

Formula: C₄₇H₅₄N₅O₉P

InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-42-40(60-45(43(42)57-7)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1

InChI key: InChIKey=JFFSFQRVIPPCBC-VKBHKTMGSA-N

SMILES: C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Synonyms:

• 2'-OMe-Bz-C Phosphoramidite
• Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
• N-Blocked-5'-O-Dmt-2'-O-Me Ced Cytosine Phosphoramidite

2'-OMe-Bz-C Phosphoramidite

CAS: 110764-78-8

Formula: C₄₇H₅₄N₅O₉P

Purity: 95%

Color and Shape: Solid

Molecular weight: 863.9335

Ref: IN-DA0083CT

2'-O-Me-C(Bz) Phosphoramidite

CAS: 110764-78-8

2'-O-Me-C(Bz) Phosphoramidite

Purity: 98%

Molecular weight: 863.93g/mol

Ref: 54-OR1030910

DMT-2'-O-methyl-rC(Bz) Phosphoramidite

CAS: 110764-78-8

Formula: C₄₇H₅₄N₅O₉P

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 863.95

Ref: 3B-D5942

2'-O-Me-C(Bz) Phosphoramidite

CAS: 110764-78-8

2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.

Formula: C₄₇H₅₄N₅O₉P

Color and Shape: Solid

Molecular weight: 863.93

Ref: TM-T37102

N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite

CAS: 110764-78-8

N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.

Formula: C₄₇H₅₄N₅O₉P

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 863.96 g/mol

Ref: 3D-PB08556