CAS 111079-19-7

Pyrimidine, 4-chloro-5-iodo-2-(methylthio)-

Description:

Pyrimidine, 4-chloro-5-iodo-2-(methylthio)- is a heterocyclic organic compound characterized by a pyrimidine ring, which consists of a six-membered ring containing two nitrogen atoms at positions 1 and 3. This specific compound features a chlorine atom at the 4-position and an iodine atom at the 5-position of the pyrimidine ring, along with a methylthio group (-S-CH3) at the 2-position. The presence of halogen substituents (chlorine and iodine) can significantly influence the compound's reactivity and potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The methylthio group may enhance the lipophilicity and biological activity of the compound. Pyrimidine derivatives are often studied for their roles in nucleic acid metabolism and as building blocks in the synthesis of various bioactive molecules. The compound's CAS number, 111079-19-7, provides a unique identifier for regulatory and research purposes, facilitating its identification in chemical databases and literature.

Formula: C₅H₄ClIN₂S

InChI: InChI=1S/C5H4ClIN2S/c1-10-5-8-2-3(7)4(6)9-5/h2H,1H3

InChI key: RPTQHLHIBGHGBF-UHFFFAOYSA-N

SMILES: CSC1=NC=C(C(=N1)Cl)I

4-Chloro-5-iodo-2-(methylthio)pyrimidine

CAS: 111079-19-7

4-Chloro-5-iodo-2-(methylthio)pyrimidine

Formula: C₅H₄ClIN₂S

Purity: 97%

Molecular weight: 286.52

Ref: 54-OR1116336

4-chloro-5-iodo-2-(methylthio)pyrimidine

CAS: 111079-19-7

Formula: C₅H₄ClIN₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 286.5211

Ref: IN-DA008Z3P

4-Chloro-5-iodo-2-(methylthio)pyrimidine

CAS: 111079-19-7

Purity: 97%

Molecular weight: 286.519989

Ref: 10-F718598

4-Chloro-5-iodo-2-(methylthio)pyrimidine

CAS: 111079-19-7

4-Chloro-5-iodo-2-(methylthio)pyrimidine is an antibacterial agent that is a synthetic analogue of the vitamin pyridoxine. It is a white, crystalline solid with a melting point of 138°C. 4-Chloro-5-iodo-2-(methylthio)pyrimidine has been shown to have activity against gram negative bacteria such as Escherichia coli and Pseudomonas aeruginosa, but not against gram positive bacteria such as Staphylococcus aureus. The drug binds to ribonucleic acid (RNA) and inhibits protein synthesis. The mechanism of action for this drug may be similar to that of pyridoxine, which inhibits the conversion of erythrocyte glutamic pyruvic transaminase to erythrocyte glutamic oxalacetic transaminase by binding to the enzyme's active site.

Formula: C₅H₄ClIN₂S

Purity: Min. 95%

Molecular weight: 286.52 g/mol

Ref: 3D-LEA07919