CymitQuimica logo

CAS 11115-82-5

:

Enduracidin

Description:
Enduracidin, with the CAS number 11115-82-5, is a naturally occurring antibiotic that belongs to the class of compounds known as cyclic lipopeptides. It is produced by certain strains of the bacterium *Micromonospora* and exhibits potent antimicrobial activity, particularly against Gram-positive bacteria. The structure of enduracidin features a cyclic peptide backbone, which is essential for its biological activity, and a fatty acid side chain that contributes to its lipophilicity. This lipophilic nature enhances its ability to penetrate bacterial membranes. Enduracidin has been studied for its potential therapeutic applications, especially in treating infections caused by resistant bacterial strains. Its mechanism of action involves inhibition of cell wall synthesis, similar to other antibiotics in its class. Additionally, enduracidin has shown promise in research for its immunomodulatory effects. However, like many antibiotics, its use may be limited by the development of resistance, necessitating ongoing research into its efficacy and potential applications in modern medicine.
Formula:Unspecified
InChI:InChI=1S/C107H138Cl2N26O31.H2O/c1-7-51(2)17-12-10-8-9-11-13-19-76(144)120-74(47-77(145)146)92(152)126-80-55(6)166-102(162)86(60-28-38-68(143)39-29-60)132-88(148)52(3)117-90(150)73(46-63-49-116-104(112)119-63)124-106(164)134-100(160)84(61-43-69(108)87(147)70(109)44-61)128-93(153)75(50-136)123-97(157)81(56-20-30-64(139)31-21-56)127-91(151)72(45-62-48-115-103(111)118-62)122-89(149)71(18-16-41-114-105(113)163)121-94(154)78(53(4)137)125-98(158)82(57-22-32-65(140)33-23-57)130-99(159)83(58-24-34-66(141)35-25-58)129-95(155)79(54(5)138)133-107(165)135(42-15-14-40-110)101(161)85(131-96(80)156)59-26-36-67(142)37-27-59;/h9,11,13,19-39,43-44,51-55,62-63,71-75,78-86,136-143,147H,7-8,10,12,14-18,40-42,45-50,110H2,1-6H3,(H,117,150)(H,120,144)(H,121,154)(H,122,149)(H,123,157)(H,125,158)(H,126,152)(H,127,151)(H,128,153)(H,129,155)(H,130,159)(H,131,156)(H,132,148)(H,133,165)(H,145,146)(H3,111,115,118)(H3,112,116,119)(H3,113,114,163)(H2,124,134,160,164);1H2/b11-9+,19-13+;
InChI key:NJCUSQKMYNTYOW-MWUYRYRWSA-N
SMILES:CCC(C)CCCC/C=C/C=C/C(=O)NC(CC(=O)O)C(=O)NC1C(OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)N(C(=O)C(NC1=O)C2=CC=C(C=C2)O)CCCCN)C(C)O)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)C(C)O)CCCNC(=O)N)CC5CNC(=N5)N)C6=CC=C(C=C6)O)CO)C7=CC(=C(C(=C7)Cl)O)Cl)CC8CNC(=N8)N)C)C9=CC=C(C=C9)O)C.O
Synonyms:
  • Enduracidin
  • Enduracidin Hydrochloride
  • Enradin
  • Enramicina
  • Enramycinum
  • Enramycinum [INN-Latin]
  • Enramycin
Found 6 products.