CAS 111470-99-6
:amlodipine besylate
Description:
Amlodipine besylate is a calcium channel blocker primarily used in the treatment of hypertension and angina. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range of approximately 6 to 8 in solution. The substance is a salt formed from amlodipine, a dihydropyridine derivative, and benzenesulfonic acid, which enhances its solubility and stability. Amlodipine besylate works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its pharmacokinetics indicate a long half-life, allowing for once-daily dosing. The compound is typically administered orally and is well-absorbed, with peak plasma concentrations occurring several hours post-ingestion. Common side effects may include peripheral edema, dizziness, and fatigue. As with any medication, it is essential to consider contraindications and potential interactions with other drugs.
Formula:C26H31ClN2O8S
InChI:InChI=1/C20H25ClN2O5.CH4O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;1-5(2,3)4/h5-8,17,23H,4,9-11,22H2,1-3H3;1H3,(H,2,3,4)
InChI key:InChIKey=ZPBWCRDSRKPIDG-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2.S(=O)(=O)(O)C1=CC=CC=C1
Synonyms:- (±)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate
- 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-3-Ethoxycarbonyl-5-Methoxycarbonyl-6-Methyl-1,4-Dihydropyridine Benzenesulfonate
- 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, benzenesulfonate (1:1)
- 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate
- 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate
- 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Benzenesulfonate (1:1)
- 3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)Methyl]-4-(2-Chlorophenyl)-6-Methyl-1,4-Dihydropyridine-3,5-Dicarboxylate Methanesulfonate (1:1)
- AM Arya 5
- Alkapress
- Alopres
- Amcard
- Amdepin
- Amdipin
- Amilo
- Amlodin
- Amlodin OD
- Amlodipine Besilate
- Amlodipine benzenesulfonate
- Amlodipine benzenesulfonate salt
- Amlodis
- Amlodopine Besilate
- Amlogard
- Amlopers 5
- Amlopin
- Amlor
- Amlosyn
- Amlovas
- Antacal
- Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1)
- Calchek
- Cardilopin
- Istin
- Lodipressin
- Lowrac
- Monopina
- Myodura
- Normodipine
- Norvas
- Norvasc
- Norvask
- Regcor
- Tensivask
- Uk 48340-26
- Vazkor
- Amlodipine besylate
- AMLODIPINE BESYLATE EPY(CRM STANDARD)
- 3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,
- AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE)
- 4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
- 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
- 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate
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Found 20 products.
Amlodipine besylate, 98+%
CAS:<p>An L-type calcium channel antagonist with potent antioxidant activity</p>Formula:C20H25ClN2O5·C6H5SO3HPurity:98+%Molecular weight:567.05AMLODIPINE BESILATE CRS
CAS:<p>AMLODIPINE BESILATE CRS</p>Formula:C20H25ClN2O5Color and Shape:AddedMolecular weight:408.8759Amlodipine besilate
CAS:Amlodipine besilateFormula:C20H25ClN2O5 / C6H6O3SPurity:72.0% / 99.9%Color and Shape:Light YellowMolecular weight:408.1452 / 158.00377Amlodipine Besylate
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C20H25ClN2O5·C6H6O3SColor and Shape:White Light Yellow PowderMolecular weight:566.14896Amlodipine Besylate
CAS:<p>Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker.</p>Formula:C26H31ClN2O8SPurity:96.67% - 99.92%Color and Shape:White PowderMolecular weight:567.05Amlodipine N-Glucose
CAS:Formula:C26H35ClN2O10Color and Shape:Pale Yellow SolidMolecular weight:571.02Amlodipine Besylate
CAS:Formula:C20H25ClN2O5·C6H6O3SColor and Shape:White To Off-White SolidMolecular weight:408.89 158.18Amlodipine besylate
CAS:Controlled ProductFormula:C20H25ClN2O5·C6H6O3SColor and Shape:NeatMolecular weight:567.05Amlodipine Besylate
CAS:Formula:C20H25ClN2O5·C6H5SO3HPurity:>98.0%(HPLC)(qNMR)Color and Shape:White to Dark green powder to crystalMolecular weight:567.05Amlodipine Besylate
CAS:<p>Applications Amlodipine Besylate is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.<br>References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);<br></p>Formula:C20H25ClN2O5·C6H6O3SColor and Shape:Light YellowMolecular weight:567.05Amlodipine besylate - Bio-X ™
CAS:<p>Amlodipine is a calcium channel blocker that is used to treat hypertension and angina. This drug inhibits the influx of calcium ions into both vascular smooth muscle and cardiac muscle.</p>Formula:C20H25ClN2O5•C6H6O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:567.05 g/molAmlodipine besylate
CAS:<p>Inhibits L-type calcium channels; anti-hypertensive; antianginal</p>Formula:C26H31ClN2O8SPurity:Min. 95%Color and Shape:PowderMolecular weight:567.05 g/mol
