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CAS 1115-70-4

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Metformin hydrochloride

Description:
Metformin hydrochloride is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications and functions by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, which is soluble in water but has limited solubility in organic solvents. Its chemical formula is C4H11N5·HCl, and it has a molecular weight of approximately 165.63 g/mol. Metformin hydrochloride is typically administered in tablet form and is known for its favorable safety profile, with gastrointestinal side effects being the most common. It is also associated with a low risk of hypoglycemia when used alone. Additionally, research has indicated potential benefits beyond glycemic control, including cardiovascular protection and weight management. As with any medication, it is essential to use metformin under medical supervision, considering contraindications and potential interactions with other drugs.
Formula:C4H11N5·ClH
InChI:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N.Cl
Synonyms:
  • 1,1-Dimethylbiguanide Hydrochloride
  • 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
  • Apo-Metformin
  • Apophage
  • Benofomin
  • Biguanide, 1,1-dimethyl-, hydrochloride
  • Biguanide, 1,1-dimethyl-, monohydrochloride
  • Dabex
  • Denkaform
  • Dextin
  • See more synonyms
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