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CAS 657-24-9

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Metformin

Description:
Metformin is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications and functions by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake and utilization. Metformin is characterized by its relatively low solubility in water, which can affect its absorption and bioavailability. The chemical formula for Metformin is C4H11N5, and it has a molecular weight of approximately 129.16 g/mol. It is typically administered in the form of hydrochloride salt, which enhances its stability and solubility. Metformin is generally well-tolerated, with gastrointestinal side effects being the most common. Importantly, it does not cause weight gain and is associated with a low risk of hypoglycemia when used alone. Additionally, Metformin has been studied for potential cardiovascular benefits and may have a role in weight management and polycystic ovary syndrome (PCOS). Its safety profile and efficacy make it a first-line treatment for type 2 diabetes.
Formula:C4H11N5
InChI:InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChI key:InChIKey=XZWYZXLIPXDOLR-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N
Synonyms:
  • 1,1-Dimethylbiguanide
  • 1-Carbamimidamido-N,N-dimethylmethanimidamide
  • 1-[Amino(dimethylamino)methylidene]guanidine
  • Biguanide, 1,1-dimethyl-
  • Cidophage
  • Dimethylbiguanide
  • Dmgg
  • Emiphage
  • Ficonax
  • Fluamine
  • See more synonyms
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