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CAS 1115-70-4

:

Metformin hydrochloride

Description:
Metformin hydrochloride is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications and functions by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, which is soluble in water but has limited solubility in organic solvents. Its chemical formula is C4H11N5·HCl, and it has a molecular weight of approximately 165.63 g/mol. Metformin hydrochloride is typically administered in tablet form and is known for its favorable safety profile, with gastrointestinal side effects being the most common. It is also associated with a low risk of hypoglycemia when used alone. Additionally, research has indicated potential benefits beyond glycemic control, including cardiovascular protection and weight management. As with any medication, it is essential to use metformin under medical supervision, considering contraindications and potential interactions with other drugs.
Formula:C4H11N5·ClH
InChI:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N.Cl
Synonyms:
  • 1,1-Dimethylbiguanide Hydrochloride
  • 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
  • Apo-Metformin
  • Apophage
  • Benofomin
  • Biguanide, 1,1-dimethyl-, hydrochloride
  • Biguanide, 1,1-dimethyl-, monohydrochloride
  • Dabex
  • Denkaform
  • Dextin
  • See more synonyms
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Found 24 products.
  • Metformin Hydrochloride

    CAS:
    Formula:C4H11N5·HCl
    Purity:>98.0%(T)(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:165.63

    Ref: 3B-M2009

    25g
    77.00€
    100g
    215.00€
  • 1,1-Dimethylbiguanide hydrochloride

    CAS:
    1,1-Dimethylbiguanide hydrochloride (HCl), or metformin HCl, 1115-70-4, is the salt form of the biguanide with antineoplastic and antihyperglycemic properties. Learn more.
    Formula:C4H12ClN5
    Color and Shape:White, Crystalline powder
    Molecular weight:165.63

    Ref: 02-J63361

    5g
    46.00€
    25g
    129.00€
    100g
    320.00€
  • Ref: 61-AMP0056.00-01

    1ml
    240.00€
  • Metformin Hydrochloride

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR0056.00

    10mg
    358.00€
  • METFORMIN HYDROCHLORIDE CRS

    CAS:
    METFORMIN HYDROCHLORIDE CRS
    Formula:C4H12ClN5
    Color and Shape:Added Modified
    Molecular weight:165.6246

    Ref: 41-M0605000

    50mg
    132.00€
  • Metformin for system suitability

    CAS:
    Metformin for system suitability
    Color and Shape:White

    Ref: 47-1296

    10mg
    211.00€
  • Metformin hydrochloride

    CAS:
    Metformin hydrochloride
    Formula:C4H12ClN5
    Purity:100%
    Color and Shape:White
    Molecular weight:165.07812

    Ref: 47-227

    100mg
    242.00€
  • Metformin Hydrochloride

    CAS:
    Non-aromatic imines and their derivatives; salts thereof, nesoi
    Formula:C4H11N5·HCl
    Color and Shape:White Off-White Powder
    Molecular weight:165.62
  • Metformin hydrochloride (mM/ml)

    CAS:
    Formula:C4H12ClN5
    Purity:97%
    Color and Shape:Solid
    Molecular weight:165.6246

    Ref: IN-DA003RHI

    5g
    20.00€
    10g
    20.00€
    25g
    24.00€
    50g
    28.00€
    100g
    31.00€
    500g
    72.00€
  • Metformin hydrochloride

    CAS:
    Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.
    Formula:C4H12ClN5
    Purity:97.53% - 99.97%
    Color and Shape:White Or Almost White Crystals Solid Crystalline
    Molecular weight:165.63

    Ref: TM-T0740

    100mg
    37.00€
    500mg
    80.00€
    1g
    92.00€
    5g
    268.00€
  • Metformin hydrochloride

    CAS:
    Metformin hydrochloride
    Purity:≥95%
    Molecular weight:165.63g/mol

    Ref: 54-BUP17373

    100mg
    53.00€
    500mg
    116.00€
    1g
    149.00€
    5g
    402.00€
  • 1,1-Dimethylbiguanide hydrochloride

    CAS:
    1,1-Dimethylbiguanide hydrochloride
    Formula:C4H11N5·ClH
    Purity:97%
    Color and Shape: white solid
    Molecular weight:165.62g/mol

    Ref: 54-OR322044

    10g
    32.00€
    25g
    36.00€
    100g
    80.00€
  • Metformin HCl

    CAS:
    Formula:C4H11N5·HCl
    Color and Shape:White To Off-White Solid
    Molecular weight:129.17 36.46

    Ref: 4Z-M-422

    5mg
    To inquire
    100mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
  • Metformin hydrochloride, EP grade

    CAS:
    Formula:C4H11N5·HCl
    Purity:98.5 - 101.0 % (dried substance)
    Color and Shape:White or almost white crystals
    Molecular weight:165.62

    Ref: 7W-GP1221

    ne
    To inquire
  • Metformin hydrochloride

    CAS:
    Formula:C4H11N5·HCl
    Purity:(Titration) 98.0 - 102.0 % (dried basis)
    Color and Shape:White or almost white crystalline powder
    Molecular weight:165.62

    Ref: 7W-GP2747

    5g
    35.00€
    25g
    83.00€
  • Metformin Hydrochloride

    CAS:
    Formula:C4H11N5·ClH
    Color and Shape:Neat
    Molecular weight:165.62

    Ref: 86-MM0056.00

    500mg
    1,335.00€
  • Metformin Hydrochloride

    CAS:
    Formula:C4H11N5·ClH
    Color and Shape:Neat
    Molecular weight:165.62

    Ref: 04-C14956000

    250mg
    To inquire
  • N1,N1-Dimethylbiguanide hydrochloride

    CAS:
    Formula:C4H12ClN5
    Purity:95%
    Color and Shape:Solid
    Molecular weight:165.63

    Ref: 10-F463363

    1g
    12.00€
    25g
    12.00€
    100g
    20.00€
    500g
    71.00€
    1kg
    102.00€
  • Metformin Impurity 13

    CAS:
    Formula:C4H7N5
    Color and Shape:White To Off-White Solid
    Molecular weight:125.14

    Ref: 4Z-M-4226

    5mg
    To inquire
    10mg
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    25mg
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    50mg
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    100mg
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  • Metformin Hydrochloride

    CAS:
    Formula:C4H11N5HCl
    Molecular weight:129.17 : 36.46

    Ref: ST-EA-CP-M3008

    10mg
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    25mg
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    50mg
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    100mg
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  • Metformin Hydrochloride

    Controlled Product
    CAS:

    Applications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner.
    References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)

    Formula:C4H11N5·ClH
    Color and Shape:Neat
    Molecular weight:165.62

    Ref: TR-M258815

    1g
    103.00€
    5g
    108.00€
    100g
    269.00€
  • Metformin Hydrochloride

    CAS:
    Formula:C4H11N5·ClH

    Ref: TR-TRC-M258815

    1g
    To inquire
    100g
    To inquire
    5g
    107.00€
  • Metformin HCl - Bio-X ™

    CAS:
    Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.
    Formula:C4H11N5•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:165.62 g/mol

    Ref: 3D-BM164663

    10mg
    135.00€
    50mg
    207.00€
  • Metformin HCl

    CAS:
    Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.
    Formula:C4H12ClN5
    Color and Shape:White Powder
    Molecular weight:165.62 g/mol

    Ref: 3D-FM25131

    500g
    322.00€
    1kg
    454.00€
    2kg
    673.00€
    5kg
    1,020.00€
    10kg
    1,502.00€