CAS 1115-70-4

Metformin hydrochloride

Description:

Metformin hydrochloride is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications and functions by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, which is soluble in water but has limited solubility in organic solvents. Its chemical formula is C4H11N5·HCl, and it has a molecular weight of approximately 165.63 g/mol. Metformin hydrochloride is typically administered in tablet form and is known for its favorable safety profile, with gastrointestinal side effects being the most common. It is also associated with a low risk of hypoglycemia when used alone. Additionally, research has indicated potential benefits beyond glycemic control, including cardiovascular protection and weight management. As with any medication, it is essential to use metformin under medical supervision, considering contraindications and potential interactions with other drugs.

Formula: C₄H₁₁N₅·ClH

InChI: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H

InChI key: InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N

SMILES: C(NC(=N)N)(N(C)C)=N.Cl

Synonyms:

• 1,1-Dimethylbiguanide Hydrochloride
• 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
• Apo-Metformin
• Apophage
• Benofomin
• Biguanide, 1,1-dimethyl-, hydrochloride
• Biguanide, 1,1-dimethyl-, monohydrochloride
• Dabex
• Denkaform
• Dextin
• Diabefagos
• Diabetmim
• Diabetmin
• Diabetosan
• Diabex
• Diaformin
• Dialon
• Diformin
• Diformin Retard
• Dimefor
• Fornidd
• Fortamet
• Geamet
• Glifage
• Glucaminol
• Glucofago
• Glucoform
• Glucoformin
• Glucomet
• Glucomin
• Glucomine
• Gluconil
• Glucophage
• Glucophage 850
• Glucophage Forte
• Glucophage Retard
• Glucophage SR
• Glucophage XR
• Glucophage-Mite
• Gludepatic
• Glufor
• Gluformin
• Glumeformin
• Glumetza
• Glumin
• Glumin XR
• Glupermin
• Glyceriphage
• Glyciphage
• Glycon
• Glyformin
• Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
• La 6023
• Meguan
• Melbin
• Metforal
• Metformin Hydrochloride
• Metgluco
• Metomin
• Miformin
• N,N-Dimethylbiguanide hydrochloride
• N,N-Dimethylbiguanidine monohydrochloride
• N,N-Dimethylbiguanidinium chloride
• N¹,N¹-Dimethylbiguanide hydrochloride
• Neodipa
• Obimat-SR
• Orabet
• Riomet
• Siamformet

Metformin Hydrochloride

CAS: 1115-70-4, 657-24-9

Formula: C₄H₁₁N₅·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 165.63

Ref: 3B-M2009

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride (HCl), or metformin HCl, 1115-70-4, is the salt form of the biguanide with antineoplastic and antihyperglycemic properties. Learn more.

Formula: C₄H₁₂ClN₅

Color and Shape: White, Crystalline powder

Molecular weight: 165.63

Ref: 02-J63361

Metformin Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 1115-70-4

Color and Shape: Single Solution

Ref: 61-AMP0056.00-01

Metformin Hydrochloride

CAS: 1115-70-4

Color and Shape: Neat

Ref: 61-FOR0056.00

METFORMIN HYDROCHLORIDE CRS

CAS: 1115-70-4

METFORMIN HYDROCHLORIDE CRS

Formula: C₄H₁₂ClN₅

Color and Shape: Powder

Molecular weight: 165.6246

Ref: 41-M0605000

Metformin for system suitability

CAS: 1115-70-4, 118632-64-7, 99-76-3

Metformin for system suitability

Color and Shape: White

Ref: 47-1296

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Formula: C₄H₁₂ClN₅

Purity: 100%

Color and Shape: White

Molecular weight: 165.07812

Ref: 47-227

Metformin Hydrochloride

CAS: 1115-70-4

Non-aromatic imines and their derivatives; salts thereof, nesoi

Formula: C₄H₁₁N₅·HCl

Color and Shape: White Off-White Powder

Molecular weight: 129.10145

Ref: 45-1396309

Metformin hydrochloride (mM/ml)

CAS: 1115-70-4

Formula: C₄H₁₂ClN₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 165.6246

Ref: IN-DA003RHI

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.

Formula: C₄H₁₂ClN₅

Purity: 97.53% - 99.97%

Color and Shape: White Or Almost White Crystals Solid Crystalline

Molecular weight: 165.63

Ref: TM-T0740

1,1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

1,1-Dimethylbiguanide hydrochloride

Formula: C₄H₁₁N₅·ClH

Purity: 97%

Color and Shape: white solid

Molecular weight: 165.62g/mol

Ref: 54-OR322044

Metformin hydrochloride, EP grade

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Purity: 98.5 - 101.0 % (dried substance)

Color and Shape: White or almost white crystals

Molecular weight: 165.62

Ref: 7W-GP1221

Metformin HCl

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 129.17 36.46

Ref: 4Z-M-422

Metformin hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·HCl

Purity: (Titration) 98.0 - 102.0 % (dried basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 165.62

Ref: 7W-GP2747

Metformin hydrochloride

CAS: 1115-70-4

Metformin hydrochloride

Purity: ≥95%

Molecular weight: 165.63g/mol

Ref: 54-BUP17373

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·ClH

Color and Shape: Neat

Molecular weight: 165.62

Ref: 04-C14956000

N1,N1-Dimethylbiguanide hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₂ClN₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 165.63

Ref: 10-F463363

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅·ClH

Color and Shape: Neat

Molecular weight: 165.62

Ref: 86-MM0056.00

Metformin Impurity 13

CAS: 1115-70-4

Formula: C₄H₇N₅

Color and Shape: White To Off-White Solid

Molecular weight: 125.14

Ref: 4Z-M-4226

Metformin Hydrochloride

Controlled Product

CAS: 1115-70-4

Applications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner.
References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)

Formula: C₄H₁₁N₅·ClH

Color and Shape: White

Molecular weight: 165.62

Ref: TR-M258815

Metformin Hydrochloride

CAS: 1115-70-4

Formula: C₄H₁₁N₅HCl

Molecular weight: 129.17 : 36.46

Ref: ST-EA-CP-M3008

Metformin HCl - Bio-X ™

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Formula: C₄H₁₁N₅•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.62 g/mol

Ref: 3D-BM164663

Metformin HCl

CAS: 1115-70-4

Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.

Formula: C₄H₁₂ClN₅

Color and Shape: White Powder

Molecular weight: 165.62 g/mol

Ref: 3D-FM25131