CAS 111540-00-2

STA-21

Description:

STA-21, with the CAS number 111540-00-2, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain protein interactions, specifically targeting the heat shock protein 90 (Hsp90) pathway. This inhibition can disrupt the function of various client proteins involved in cancer cell proliferation and survival, making STA-21 a candidate for cancer treatment research. The compound exhibits a specific binding affinity, which is crucial for its effectiveness in modulating biological pathways. Additionally, STA-21 has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), which are essential for evaluating its potential as a drug. Its chemical structure and properties contribute to its biological activity, and ongoing research aims to further elucidate its mechanisms and optimize its therapeutic efficacy.

Formula: C₁₉H₁₄O₄

InChI: InChI=1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3

InChI key: ZAWXOCUFQSQDJS-UHFFFAOYSA-N

SMILES: CC1CC2=C(C(=O)C1)C3=C(C=C2)C(=O)C4=C(C3=O)C=CC=C4O

Synonyms:

• 8-HYDROXY-3-METHYL-1,2,3,4,7,12-HEXAHYDROTETRAPHENE-1,7,12-TRIONE
• Ochromycinone (STA-21)
• STA 21
• (Rac)-STA-21
• STA-21 >=95% (HPLC)

Ochromycinone

CAS: 111540-00-2

Ochromycinone

Formula: C₁₉H₁₄O₄

Purity: 98%

Molecular weight: 306.31

Ref: 54-OR1023793

Ochromycinone

CAS: 111540-00-2

Ochromycinone

Purity: ≥95%

Molecular weight: 306.31g/mol

Ref: 54-BUP03486

8-Hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione

CAS: 111540-00-2

Formula: C₁₉H₁₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 306.3121

Ref: IN-DA0092WE

Ochromycinone

CAS: 111540-00-2

8-Hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione

Formula: C₁₉H₁₄O₄

Purity: 98%

Molecular weight: 306.31

Ref: IN-DG764860

Ochromycinone

CAS: 111540-00-2

Ochromycinone (STA 21) is a selective STAT3 inhibitor.

Formula: C₁₉H₁₄O₄

Purity: 99.21%

Color and Shape: Yellow Solid

Molecular weight: 306.3121

Ref: TM-T6995

8-Hydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione

CAS: 111540-00-2

Purity: 98%

Molecular weight: 306.3169861

Ref: 10-F870352

Ochromycinone (STA-21)

CAS: 111540-00-2

Ochromycinone is a neurotrophic factor that has been shown to inhibit the growth of skin cancer cells. It has been shown to induce the production of neurotrophic factors, which are proteins that promote neuronal survival and growth. Ochromycinone also has biological properties that have been associated with cellular transformation and tumorigenesis. This protein binds to dinucleotide phosphate (DNP) and inhibits polymerase chain reaction (PCR) by binding to DNA in vitro. Ochromycinone may be a potential drug target for infectious diseases such as HIV or herpes simplex virus infections. It has also been shown to inhibit Toll-like receptor (TLR) signaling pathways in experimental models.

Formula: C₁₉H₁₄O₄

Purity: Min. 95%

Molecular weight: 306.31 g/mol

Ref: 3D-LEA54000