CAS 111974-72-2
:Quetiapine fumarate
Description:
Quetiapine fumarate is an atypical antipsychotic medication primarily used to treat schizophrenia, bipolar disorder, and major depressive disorder. It is a salt form of quetiapine, which is a dibenzothiazepine derivative. The compound exhibits a complex pharmacological profile, acting as an antagonist at various neurotransmitter receptors, including serotonin (5-HT2A) and dopamine (D2) receptors, which contributes to its therapeutic effects. Quetiapine fumarate is typically administered orally and is known for its relatively favorable side effect profile compared to older antipsychotics, although it can still cause sedation, weight gain, and metabolic changes. The substance is characterized by its solubility in water and organic solvents, which facilitates its formulation in various dosage forms. Its chemical structure includes a thienobenzodiazepine core, contributing to its pharmacological activity. As with any medication, careful monitoring is essential to manage potential side effects and ensure effective treatment outcomes.
Formula:C21H25N3O2SC4H4O4
InChI:InChI=1S/C21H25N3O2S.C4H4O4/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChI key:InChIKey=VRHJBWUIWQOFLF-WLHGVMLRSA-N
SMILES:C(COCCO)N1CCN(C=2C=3C(SC=4C(N2)=CC=CC4)=CC=CC3)CC1.C(=C/C(O)=O)\C(O)=O
Synonyms:- 2-[2-(4-Dibenzo[B,F][1,4]Thiazepin-11-Yl-1-Piperazinyl)Ethoxy]Ethanol Hemifumarate
- 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol (2E)-but-2-enedioate (salt)
- Dibenzo[b,f][1,4]thiazepine, ethanol deriv.
- Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1)
- Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1) (salt)
- Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (E)-2-butenedioate (2:1) (salt)
- Ici 204636
- Kwetaplex
- Loquen
- Quetiapine Fumarate Main Intermediates
- Quetiapine hemifumarate
- Quetinapine Fumarate
- Quetros
- Quitpin
- Seroquel
- Zd 5077
- See more synonyms
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Found 20 products.
Quetiapine Hemifumarate
CAS:Formula:C21H25N3O2SC4H4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:441.55QUETIAPINE FUMARATE CRS
CAS:QUETIAPINE FUMARATE CRSFormula:C6H6F2N2Color and Shape:PowderMolecular weight:144.122Quetiapine fumarate
CAS:Quetiapine fumarateFormula:C46H54N6O8S2Purity:99.7%Color and Shape:WhiteMolecular weight:882.34446Quetiapine Fumarate
CAS:<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Formula:(C21H25N3O2S)2·C4H4O4Color and Shape:White Off-White Crystalline PowderMolecular weight:766.3335Quetiapine hemifumarate
CAS:Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar I/II depression,.Formula:C46H54N6O8S2Purity:99.32% - >99.99%Color and Shape:White Crystalline SolidMolecular weight:883.09Quetiapine Hemifumarate
CAS:Formula:C21H25N3O2S·5C4H4O4Color and Shape:White To Off-White SolidMolecular weight:383.51 0.5*116.07Quetiapine fumarate
CAS:Formula:C21H25N3O2S·5C4H4O4Purity:≥ 98.0% (anhydrous basis)Color and Shape:White or almost white powderMolecular weight:441.54Quetiapine hemifumarate
CAS:Controlled Product<p>Quetiapine hemifumarate is an antipsychotic drug that blocks receptors for dopamine, serotonin, and adrenergic neurotransmitters. It is used to treat schizophrenia and other disorders such as bipolar disorder. Quetiapine has been shown to be effective in clinical trials. The fumarate salt of quetiapine is the form of the drug that is used in these trials. Serum prolactin levels were found to be significantly lower in patients who received the fumarate salt than those who received a placebo. Quetiapine hemifumarate may potentiate the effects of other drugs by inducing their metabolism via CYP3A4 or CYP2D6 enzymes, which are also responsible for its own metabolism. This drug can interact with other drugs such as risperidone, olanzapine, and clozapine due to its atypical nature. Quetiapine hemifumarate has side effects</p>Formula:C21H25N3O2S•(C4H4O4)0Purity:Min. 95%Color and Shape:PowderMolecular weight:441.54 g/mol
