CAS 111974-72-2: Quetiapine fumarate

Description:Quetiapine fumarate is an atypical antipsychotic medication primarily used to treat schizophrenia, bipolar disorder, and major depressive disorder. It is a salt form of quetiapine, which is a dibenzothiazepine derivative. The compound exhibits a complex pharmacological profile, acting as an antagonist at various neurotransmitter receptors, including serotonin (5-HT2A) and dopamine (D2) receptors, which contributes to its therapeutic effects. Quetiapine fumarate is typically administered orally and is known for its relatively favorable side effect profile compared to older antipsychotics, although it can still cause sedation, weight gain, and metabolic changes. The substance is characterized by its solubility in water and organic solvents, which facilitates its formulation in various dosage forms. Its chemical structure includes a thienobenzodiazepine core, contributing to its pharmacological activity. As with any medication, careful monitoring is essential to manage potential side effects and ensure effective treatment outcomes.

Formula:C₂₁H₂₅N₃O₂SC₄H₄O₄

InChI:InChI=1S/C21H25N3O2S.C4H4O4/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key:InChIKey=VRHJBWUIWQOFLF-WLHGVMLRSA-N

SMILES:O=C(O)C=CC(=O)O.OCCOCCN1CCN(C2=NC=3C=CC=CC3SC=4C=CC=CC42)CC1

Synonyms:
2-[2-(4-Dibenzo[B,F][1,4]Thiazepin-11-Yl-1-Piperazinyl)Ethoxy]Ethanol Hemifumarate
2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol (2E)-but-2-enedioate (salt)
Dibenzo[b,f][1,4]thiazepine, ethanol deriv.
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1)
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (2E)-2-butenedioate (2:1) (salt)
Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, (E)-2-butenedioate (2:1) (salt)
Ici 204636
Kwetaplex
Loquen
Quetiapine Fumarate Main Intermediates
See more synonyms
Quetiapine hemifumarate
Quetinapine Fumarate
Quetros
Quitpin
Seroquel
Zd 5077
Zm 204636

Found 16 products.

Product data	Purity	Price range	Estimated delivery
Quetiapine fumarate CRS REF: 41-Y0001657CAS: 111974-72-2	- - -	115.00 €	Wed 09 Apr 25
Quetiapine for system suitability CRS REF: 41-Y0001419CAS: 111974-72-2	- - -	115.00 €	Wed 09 Apr 25
Quetiapine fumarate REF: 47-1215CAS: 111974-72-2	99.7%	242.00 €	Wed 09 Apr 25
Quetiapine Fumarate REF: 45-1592704CAS: 111974-72-2	- - -	463.00 €	Thu 10 Apr 25
Quetiapine hemifumarate REF: TM-T6241CAS: 111974-72-2	100% - 99.59%	35.00 €~52.00 €	Fri 11 Apr 25
Quetiapine (hemifumarate) REF: 54-OR1029302CAS: 111974-72-2	- - -	32.00 €~1,284.00 €	Mon 14 Apr 25
Quetiapine Hemifumarate REF: 4Z-Q-016CAS: 111974-72-2	- - -	225.00 €~977.00 €	Mon 14 Apr 25
Quetiapine fumarate REF: 7W-GP9577CAS: 111974-72-2	≥ 98.0% (anhydrous basis)	42.00 €~268.00 €	Mon 14 Apr 25
Quetiapine-d8 Hemifumarate (piperazine-d8) ( REF: 3U-D7799CAS: 111974-72-2 1435938-24-1	98 atom % D	757.00 €~1,260.00 €	Tue 15 Apr 25
Quetiapine Fumarate REF: 86-MM1130.00-0250CAS: 111974-72-2	- - -	1,447.00 €	Mon 14 Apr 25
Quetiapine hemifumarate REF: AC-46240CAS: 111974-72-2	- - -	68.00 €~227.00 €	Mon 14 Apr 25
Quetiapine fumarate REF: 04-C16696000CAS: 111974-72-2	- - -	157.00 €	Mon 14 Apr 25
Quetiapine Hemifumarate REF: 3B-Q0092CAS: 111974-69-7 111974-72-2	>98.0%(T)(HPLC)	90.00 €~295.00 €	Mon 14 Apr 25
Quetiapine Fumarate RS REF: 2K-1047200021CAS: 111974-72-2	- - -	To inquire	Mon 21 Apr 25
Quetiapine Hemifumarate REF: TR-Q510000CAS: 111974-72-2	- - -	181.00 €~210.00 €	Mon 21 Apr 25
Quetiapine hemifumarate REF: 3D-ID57889CAS: 111974-72-2	Min. 95%	164.00 €~2,681.00 €	Tue 10 Jun 25