CAS 112022-83-0: (R)-2-Methyl-CBS-oxazaborolidine

Description: (R)-2-Methyl-CBS-oxazaborolidine is a chiral organoboron compound that serves as a catalyst in various asymmetric synthesis reactions, particularly in the formation of carbon-carbon bonds. This compound features a boron atom coordinated to an oxazaborolidine framework, which contributes to its unique reactivity and selectivity in catalysis. The presence of the methyl group at the 2-position enhances its steric and electronic properties, making it effective for enantioselective reactions. Its chiral nature allows it to preferentially favor the formation of one enantiomer over another, which is crucial in the synthesis of pharmaceuticals and other fine chemicals. The compound is typically used in reactions such as the reduction of ketones and aldehydes, where it can facilitate the formation of alcohols with high enantiomeric excess. Additionally, (R)-2-Methyl-CBS-oxazaborolidine is valued for its stability and ease of handling, making it a popular choice in synthetic organic chemistry. Its applications extend to various fields, including medicinal chemistry and materials science, where chirality plays a significant role in the properties and activities of the resulting compounds.

Formula: C₁₈H₂₀BNO

InChI: InChI=1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1

InChI key: InChIKey=VMKAFJQFKBASMU-QGZVFWFLSA-N

SMILES: O1B(N2CCCC2C1(C=3C=CC=CC3)C=4C=CC=CC4)C

Synonyms:

• (3AR)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-1-methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R)-(+)-2-Methyl-CBS-oxazaborolindine
• (R)-1-Methyl,3,3-Diphenyl-TETRAHYDRO-PYRROLO(1,2-C)(1,3,2)oxazaborole
• (R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c]-[1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
• (R)-5,5-Diphenyl-2-Methyl-3,4-PROPANO-1,3,2-oxazaborolidine
• (R)-Me-CBS
• (R)-Me-Corey-Bakshi-Shibata reagent
• (R)-Methyl oxazaborolidine
• (R)-Methyl-CBS
• (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R-Methyl-Corey-Bakshi-Shibata catalyst
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (3aR)-
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (R)-
• ALPHA,ALPHA-Diphenyl-D-PROLINOL METHYLBORONIC ACID CYCL-AMIDE-ESTER
• (R)-(+)-2-Methyl-CBS-oxazaborolidine

(R)-2-Methyl-CBS-oxazaborolidine, 1M soln. in toluene

CAS: 112022-83-0

(R)-2-Methyl-CBS-oxazaborolidine is used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective …

• Formula: C₁₈H₂₀BNO
• Color and Shape: Clear colorless to pale yellow, Liquid
• Molecular weight: 277.17

CALLERY™ (R)-Methyl oxazaborolidine, 1M in toluene

CAS: 112022-83-0

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine] (R)-CBS Catalyst

• Formula: C₁₈H₂₀BNO
• Color and Shape: colorless to amber liq.
• Molecular weight: 277.17

(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

CAS: 112022-83-0

• Formula: C₁₈H₂₀BNO
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 277.1685

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 1mol/L in Toluene

CAS: 112022-83-0

• Formula: C₁₈H₂₀BNO
• Purity: 0.97
• Color and Shape: brown liquid
• Molecular weight: 277.17g/mol

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (ca. 1mol/L in Toluene)

CAS: 112022-83-0

• Formula: C₁₈H₂₀BNO
• Color and Shape: Colorless to Light yellow clear liquid
• Molecular weight: 277.17

(R)-Methyl oxazaborolidine 1M in toluene

CAS: 112022-83-0

• Purity: 95.0%
• Color and Shape: Liquid, Clear
• Molecular weight: 369.32000732421875

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine

CAS: 112022-83-0

• Formula: C₁₈H₂₀BNO
• Purity: >97.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 277.17

(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS: 112022-83-0

(R)-(+)-2-Methyl-CBS-oxazaborolidine is a dpp-iv inhibitor that is a β-unsaturated ketone. It has been shown to …

• Formula: C₁₈H₂₀BNO
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 277.17 g/mol

(R)-(+)-2-Methyl-CBS-oxazaborolidine, 1M solution in toluene

CAS: 108-88-3 112022-83-0

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₈H₂₀BNO
• Color and Shape: Solution, Colorless to amber
• Molecular weight: 277.17

(R)-(+)-2-Methyl-CBS-oxazaborolidine, 1M solution in toluene, AcroSeal™

CAS: 108-88-3 112022-83-0

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₈H₂₀BNO
• Color and Shape: Liquid, Colorless to amber
• Molecular weight: 277.17

(R) -2-Methyl-CBS-oxazaborolidine - 1M solution in Toluene

CAS: 112022-83-0

(R) -2-Methyl-CBS-oxazaborolidine is a chiral, optically pure 2-methyl-CBS oxazaborolidine. It has been used as a …

• Formula: C₁₈H₂₀BNO
• Purity: Min. 95%
• Color and Shape: Colourless To Yellow Liquid
• Molecular weight: 277.17 g/mol