CAS 1120333-38-1

Formula: C25H32N4O4S2

InChI: InChI=1S/C25H32N4O4S2/c1-34(30,31)29-9-7-22(8-10-29)26-24-16-19(18-28-11-13-35(32,33)14-12-28)15-21-17-23(27-25(21)24)20-5-3-2-4-6-20/h2-6,15-17,22,26-27H,7-14,18H2,1H3

InChI key: OXROWZRDUZOTSG-UHFFFAOYSA-N

SMILES: CS(=O)(=O)N1CCC(CC1)NC2=CC(=CC3=C2NC(=C3)C4=CC=CC=C4)CN5CCS(=O)(=O)CC5

NecroX-2

CAS: 1120333-38-1

NecroX-2

Formula: C₂₅H₃₂N₄O₄S₂

Purity: ≥95%

Molecular weight: 516.68

Ref: 54-BUP22191

5-[(1,1-Dioxido-4-thiomorpholinyl)methyl]-N-[1-(methylsulfonyl)-4-piperidinyl]-2-phenyl-1H-indol-7-amine

CAS: 1120333-38-1

Purity: 98%

Ref: IN-DA01FG9U

NecroX-2

CAS: 1120333-38-1

NecroX-2 is a cell-permeable necrosis inhibitor with antioxidant properties. NecroX-2 selectively suppresses necrotic cell death triggered by oxidative stress. NecroX-2 does not confer protection against apoptosis induced by staurosporine or etoposide but shows protective effects under conditions such as cold shock, hypoxia, and oxidative stress in vitro.

Formula: C₂₅H₃₂N₄O₄S₂

Purity: 97.12%

Color and Shape: Solid

Molecular weight: 516.68

Ref: TM-T202375

5-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]-N-(1-methylsulfonylpiperidin-4-yl)-2-phenyl-1H-indol-7-ae

CAS: 1120333-38-1

5-[(1,1-Dioxo-1,4-thiazinan-4-yl)methyl]-N-(1-methylsulfonylpiperidin-4-yl)-2-phenyl-1Hindol-7a(2H)-one is a potent and selective inhibitor of voltage gated sodium channels. It has been shown to inhibit the activity of recombinant human Na v 1.4 channels in a reversible fashion with an IC 50 value of 0.14 μM.

Formula: C₂₅H₃₂N₄O₄S₂

Purity: Min. 95%

Molecular weight: 516.7 g/mol

Ref: 3D-VUB33338