CAS 1121-22-8

(±)-trans-1,2-Diaminocyclohexane

Description:

(±)-trans-1,2-Diaminocyclohexane, with the CAS number 1121-22-8, is a bicyclic organic compound characterized by the presence of two amine functional groups attached to a cyclohexane ring. This compound exists as a racemic mixture, meaning it contains equal amounts of both enantiomers, which are non-superimposable mirror images of each other. The trans configuration indicates that the amine groups are positioned on opposite sides of the cyclohexane ring, contributing to its unique stereochemistry. It is a colorless to pale yellow solid at room temperature and is soluble in water and various organic solvents. The presence of the amine groups allows for hydrogen bonding, which can influence its reactivity and interactions with other molecules. (±)-trans-1,2-Diaminocyclohexane is often used in organic synthesis, particularly in the preparation of ligands for coordination chemistry and as a building block in pharmaceuticals. Its ability to form chelates with metal ions makes it valuable in catalysis and materials science.

Formula: C₆H₁₄N₂

InChI: InChI=1/C6H14N2/c7-5-3-1-2-4-6(5)8/h5-6H,1-4,7-8H2/t5-,6-/m0/s1

InChI key: InChIKey=SSJXIUAHEKJCMH-IOMOGOHMNA-N

SMILES: N[C@H]1[C@H](N)CCCC1

Synonyms:

• (+/-)-trans-1,2-Cyclohexanediamine
• (1R,2R)-rel-1,2-Cyclohexanediamine
• (1S,2S)-cyclohexane-1,2-diamine
• 1,2-Cyclohexanediamine, (1R,2R)-rel-
• 1,2-Cyclohexanediamine, trans-
• 1,2-trans-Diaminocyclohexane
• Cyclohexane-1,2-Diamine
• S,S-Cyclohexanediamine
• Trans-(L)-1,2-Diaminecyclohexane
• rel-(1R,2R)-1,2-Cyclohexanediamine
• rel-(1R,2R)-Cyclohexane-1,2-diamine
• trans-N,N′-1,2-Cyclohexanediamine
• trans-dl-1,2-Diaminocyclohexane
• trans-1,2-Diaminocyclohexane
• (+/-)-trans-1,2-Diaminocyclohexane
• trans-1,2-Diaminocyclohexane
• Cyclohexanediamine
• (n)-trans-1,2-cyclohexanediamine
• 1,2-TRAMS-DIAMINOCYCLOHEXANE
• trans-1,2-Diaminocyclohexane(Racemic)
• Diaminocyclohexane,trans-1,2-
• trans-1,2-Cyclohexaneiamine
• (n)-trans-1,2-diaminocyclohexane

trans-1,2-Cyclohexanediamine

CAS: 1121-22-8

Formula: C₆H₁₄N₂

Purity: >97.0%(GC)(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 114.19

Ref: 3B-C1120

(+/-)-trans-1,2-Diaminocyclohexane, 99%

CAS: 1121-22-8

()-trans-1,2-Diaminocyclohexane is employed in the synthesis of macrocyclic [3+3] hexa Schiff base. It also plays an important role in the preparation of multidentate ligands, chiral auxiliaries and chiral stationary phases. Further, it is used to prepare [2+2] macrocyclization by reacting with alip

Formula: C₆H₁₄N₂

Purity: 99%

Color and Shape: Liquid, Clear or slightly hazy colorless to pale yellow

Molecular weight: 114.19

Ref: 02-L06626

trans-1,2-Diaminocyclohexane

CAS: 1121-22-8

Formula: C₆H₁₄N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 114.1888

Ref: IN-DA00HCCM

(+/-)-trans-1,2-Diaminocyclohexane

CAS: 1121-22-8

Formula: C₆H₁₄N₂

Purity: ≥ 98.0%

Color and Shape: Colourless to light yellow liquid

Molecular weight: 114.19

Ref: 7W-GK4641

trans-1,2-Diaminocyclohexane

CAS: 1121-22-8

trans-1,2-Diaminocyclohexane

Purity: 99%

Color and Shape: Pale Yellow Liquid

Molecular weight: 114.19g/mol

Ref: 54-OR315007

trans-1,2-Diaminocyclohexane (Racemic)

CAS: 1121-22-8

Formula: C₆H₁₄N₂

Purity: 98.0%

Color and Shape: Liquid, Clear

Molecular weight: 114.192

Ref: 10-F012707

(±)-trans-1,2-Diaminocyclohexane

Controlled Product

CAS: 1121-22-8

Applications (±)-trans-1,2-Diaminocyclohexane is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, J. J., et al.: Bioorg. Med. Chem. Lett., 20, 306 (2010)

Formula: C₆H₁₄N₂

Color and Shape: Neat

Molecular weight: 114.19

Ref: TR-D416095

(+/-)-Trans-1,2-diaminocyclohexane

CAS: 1121-22-8

(+/-)-Trans-1,2-diaminocyclohexane is a chiral compound that is used in the preparation of anticancer drugs. It has been shown to inhibit cancer cell lines in a linear regression analysis and inhibits tumor growth by chelating copper ions. The 5-membered ring of the molecule forms hydrogen bonding interactions with the 3-mercaptopropionic acid. (+/-)-Trans-1,2-diaminocyclohexane binds to DNA through its chloride group and inhibits DNA synthesis by reacting with amino groups on the phosphate backbone of DNA. This reaction leads to formation of a stable covalent intermediate between (+/-)-trans-1,2-diaminocyclohexane and the 5' phosphate group on one strand of DNA. This inhibition results in decreased levels of cyclohexane ring, which prevents tumor growth.

Formula: C₆H₁₄N₂

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 114.19 g/mol

Ref: 3D-FT76176