CAS 1123837-84-2: N-[3-Fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

Description: N-[3-Fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide, with CAS number 1123837-84-2, is a complex organic compound characterized by its multi-functional structure. It features a cyclopropanedicarboxamide core, which is notable for its potential biological activity. The presence of fluorine atoms in the molecule enhances its lipophilicity and may influence its pharmacokinetic properties. The compound also contains various aromatic and heterocyclic moieties, contributing to its potential interactions with biological targets. Its methoxyethyl and amino groups suggest possible solubility in organic solvents and potential for hydrogen bonding, which can affect its reactivity and stability. This compound is likely to be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its intricate structure that may confer specific biological activities. However, detailed studies would be necessary to fully elucidate its properties and potential applications.

Formula: C₃₃H₂₉F₂N₅O₄S

InChI: InChI=1S/C33H29F2N5O4S/c1-43-15-14-36-18-20-2-8-25(38-19-20)29-17-26-30(45-29)28(10-13-37-26)44-27-9-7-23(16-24(27)35)40-32(42)33(11-12-33)31(41)39-22-5-3-21(34)4-6-22/h2-10,13,16-17,19,36H,11-12,14-15,18H2,1H3,(H,39,41)(H,40,42)

InChI key: InChIKey=WLAVZAAODLTUSW-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(SC54)C=6N=CC(=CC6)CNCCOC)C(F)=C3)CC2

Synonyms:

• MGCD 516
• N-[3-Fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• N-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• 1,1-Cyclopropanedicarboxamide, N-[3-fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-
• Sitravatinib

Sitravatinib

CAS: 1123837-84-2

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 629.6763

Sitravatinib

CAS: 1123837-84-2

Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, …

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: 98.9% - 99.74%
• Color and Shape: Solid
• Molecular weight: 629.68

Sitravatinib

CAS: 1123837-84-2

Inhibits multiple receptor tyrosine kinases (RTKs), including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl. Sitravatinib inhibits …

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 629.68 g/mol

MGCD 516

CAS: 1123837-84-2

• Formula: C₃₃H₂₉F₂N₅O₄S
• Color and Shape: Neat
• Molecular weight: 629.676