
CAS 1125593-20-5
:Formula:C28H33N5O4S
InChI:InChI=1S/C28H33N5O4S/c1-18(2)38(35,36)26-7-5-4-6-23(26)30-24-17-27(32-28-21(24)10-13-29-28)31-22-9-8-19(16-25(22)37-3)33-14-11-20(34)12-15-33/h4-10,13,16-18,20,34H,11-12,14-15H2,1-3H3,(H3,29,30,31,32)
InChI key:NMJMRSQTDLRCRQ-UHFFFAOYSA-N
SMILES:CC(C)S(=O)(=O)C1=CC=CC=C1NC2=CC(=NC3=C2C=CN3)NC4=C(C=C(C=C4)N5CCC(CC5)O)OC
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Mps1-IN-1
CAS:Mps1-IN-1 is a molecule that inhibits the mitotic checkpoint, leading to cell death. It has been shown to inhibit the localization of Mps1 in cells and leads to an accumulation of cells in metaphase. This drug also has anti-leukemic activity in vitro and it is effective against leukemia cells. Mps1-IN-1 inhibits the function of two molecules (bi-d1870) that are involved in cancer progression and metastasis. This drug has been shown to inhibit protein synthesis and cell division through the inhibition of RNA synthesis, which is necessary for translation initiation.Formula:C28H33N5O4SPurity:Min. 95%Molecular weight:535.67 g/molMps1-IN-1
CAS:Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )Formula:C28H33N5O4SPurity:99.55%Color and Shape:Yellow SolidMolecular weight:535.658




