CAS 1126745-90-1
:SILDENAFIL-D3
Description:
Sildenafil-D3, with the CAS number 1126745-90-1, is a deuterated form of sildenafil, which is primarily known for its use in treating erectile dysfunction and pulmonary arterial hypertension. The deuteration involves the substitution of hydrogen atoms with deuterium, a stable isotope of hydrogen, which can influence the pharmacokinetics and metabolic stability of the compound. Sildenafil itself functions as a phosphodiesterase type 5 (PDE5) inhibitor, enhancing the effects of nitric oxide and increasing blood flow to specific areas of the body. The characteristics of Sildenafil-D3 may include altered solubility, stability, and bioavailability compared to its non-deuterated counterpart. This modification can be beneficial in research settings, particularly in pharmacokinetic studies, as it allows for the differentiation between the drug and its metabolites in biological systems. Overall, Sildenafil-D3 retains the core pharmacological properties of sildenafil while potentially offering advantages in specific scientific applications.
Formula:C22H27D3N6O4S
Synonyms:- 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine-d3
- SILDENAFIL-D3
- 5-[2-Ethoxy-5-[[4-(Methyl-d3)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.
Sildenafil-d3 (N-methyl-d3-piperazine)
CAS:Purity:99 atom % DColor and Shape:White SolidMolecular weight:477.60Sildenafil-d3
CAS:Controlled Product<p>Stability Store in Freezer<br>Applications Labelled Sildenafil, an orally active selective type 5 cGMP phosphodiesterase inhibitor.<br>References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996), Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998),<br></p>Formula:C22D3H27N6O4SColor and Shape:WhiteMolecular weight:477.60
