CAS 1128-23-0

Reduced ascorbate

Description:

Reduced ascorbate, commonly known as ascorbic acid or vitamin C in its reduced form, is a water-soluble vitamin and antioxidant. It plays a crucial role in various biological processes, including collagen synthesis, immune function, and the absorption of iron from plant-based foods. The chemical structure of reduced ascorbate features a six-carbon lactone ring with multiple hydroxyl groups, which contribute to its reactivity and solubility in water. As an antioxidant, it helps neutralize free radicals, thereby protecting cells from oxidative stress. Reduced ascorbate is also involved in enzymatic reactions, serving as a cofactor for several important enzymes. It is generally stable under acidic conditions but can degrade in the presence of heat, light, and oxygen. In dietary sources, it is found abundantly in fruits and vegetables, particularly citrus fruits, berries, and leafy greens. Due to its essential role in human health, reduced ascorbate is often included in dietary supplements and fortified foods.

Formula: C₆H₁₀O₆

InChI: InChI=1S/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3+,4-,5+/m0/s1

InChI key: InChIKey=SXZYCXMUPBBULW-SKNVOMKLSA-N

SMILES: [C@@H](CO)(O)[C@@]1([C@H](O)[C@H](O)C(=O)O1)[H]

Synonyms:

• (3R,4S,5S)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name)
• (3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name)
• <span class="text-smallcaps">L</span>-(+)-Gulonic acid γ-lactone
• <span class="text-smallcaps">L</span>-Gulono-1,4-lactone
• <span class="text-smallcaps">L</span>-Gulono-γ-lactone
• <span class="text-smallcaps">L</span>-Gulonolactone
• Dihydroascorbic acid
• Gulonic acid, γ-lactone, <span class="text-smallcaps">L</span>-
• L(+)-Gulonic acid-γ-lactone
• L(+)-Gulono-1,4-Lactone
• L-Gulonic Gamma-Lactone
• L-Gulonic-G-Lactone
• L-Gulono-Gamma-Lactone
• L-Gulonolactone
• Reduced ascorbate
• Reduced ascorbic acid
• γ-Gulonolactone
• L-Gulono-γ-lactone
• L(+)-Gulonic Acid Gamma-Lactone
• Gulonic acid, γ-lactone, L-
• L-Gulonic Acid Gamma-Lactone

L-(+)-Gulonic Acid γ-Lactone

CAS: 1128-23-0

Formula: C₆H₁₀O₆

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 178.14

Ref: 3B-G0235

L-Gulonic acid-1,4-lactone, 95%

CAS: 1128-23-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₀O₆

Purity: 95%

Molecular weight: 178.14

Ref: 02-J66934

L(+)-Gulonic acid γ-lactone

CAS: 1128-23-0

Formula: C₆H₁₀O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 178.1400

Ref: IN-DA008R4F

L-Gulonic Acid γ-Lactone

CAS: 1128-23-0

L-Gulonic Acid γ-Lactone

Purity: 98%

Molecular weight: 178.14g/mol

Ref: 54-OR1013660

L-Gulono-1,4-lactone

CAS: 1128-23-0

L-Gulono-1,4-lactone

Purity: ≥95%

Molecular weight: 178.14g/mol

Ref: 54-BUP19093

L-Gulono-1,4-lactone

CAS: 1128-23-0

Formula: C₆H₁₀O₆

Purity: ≥ 95%

Color and Shape: White to off-white crystalline powder

Molecular weight: 178.14

Ref: 7W-GC8500

L-Gulono-1,4-lactone

CAS: 1128-23-0

L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C.

Formula: C₆H₁₀O₆

Purity: ≥95%

Color and Shape: Less Crystals Colorless Crystals

Molecular weight: 178.14

Ref: TM-T5578

L-Gulono-1,4-lactone

Controlled Product

CAS: 1128-23-0

Applications L-Gulono-1,4-lactone is a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C.
References Wolucka, B. et al.: J. Biol. Chem., 278, 47483 (2003); Heller, R. et al.: J. Biol Chem., 274, 8254 (1999);

Formula: C₆H₁₀O₆

Color and Shape: White To Off-White

Molecular weight: 178.14

Ref: TR-G855000

L-Gulonic acid-1,4-lactone

CAS: 1128-23-0

L-Gulonic acid-1,4-lactone is an ascorbic acid derivative that inhibits the production of matrix metalloproteinases (MMPs) and other enzymes. L-Gulonic acid-1,4-lactone has been shown to inhibit the activity of MMPs in hl-60 cells, which may be due to its ability to chelate metal ions, such as zinc and copper. This molecule also has a stabilizing effect on collagen type I because it prevents cross linking between lysine amino acids. The discovery process for this molecule was found by screening clones from a cDNA library with biochemical properties similar to those of ascorbic acid. This molecule has been shown to inhibit the activation of protein kinase C (PKC) and phosphorylation of extracellular signal regulated kinase (ERK). L-Gulonic acid-1,4-lactone is metabolized through plant metabolism

Formula: C₆H₁₀O₆

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 178.14 g/mol

Ref: 3D-MG06707

L-Gulono-γ-lactone

CAS: 1128-23-0

L-Gulono-gamma-lactone is a natural vitamin C metabolite that is synthesized from L-ascorbic acid in the liver. It has been shown to inhibit the oxidase and other enzymes involved in ascorbic acid metabolism, which may be due to its ability to bind to iron. L-Gulono-gamma-lactone also inhibits polymerase chain reactions in rat liver microsomes and inhibits the activities of ascorbic acid and glutathione reductase in rat hepatic tissues. This compound is not active against humans, but it has been shown to have antioxidation properties.

Formula: C₆H₁₀O₆

Molecular weight: 178.14 g/mol

Ref: 3D-G-8500

(3S,4R,5R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one

CAS: 1128-23-0

Formula: C₆H₁₀O₆

Purity: 97%

Color and Shape: Solid, White to almost white powder

Molecular weight: 178.14

Ref: 10-F233102

L-Gulono-1,4-Lactone extrapure, 98%

CAS: 1128-23-0

Formula: C₆H₁₀O₆

Purity: min. 98%

Color and Shape: White to off - white, Crystalline powder

Molecular weight: 178.14

Ref: SR-97514

L-Gulono-1,4-lactone-13C6

Controlled Product

CAS: 1128-23-0

Applications Isotope labelled L-Gulono-1,4-lactone, a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C. A cleavage product of L-gulonolactone oxidase
References Wolucka, B. et al.: J. Biol. Chem., 278, 47483 (2003); Heller, R. et al.: J. Biol Chem., 274, 8254 (1999);

Formula: C₆H₁₀O₆

Color and Shape: Neat

Molecular weight: 184.1

Ref: TR-G855002