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CAS 112883-42-8

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Fmoc-N-Methyl-L-Norleucine

Description:
Fmoc-N-Methyl-L-Norleucine is a synthetic amino acid derivative commonly used in peptide synthesis and research. It features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized for the protection of amino groups during solid-phase peptide synthesis. The presence of the N-methyl group enhances its lipophilicity and can influence the conformational properties of peptides. L-Norleucine, the core structure, is a non-polar, aliphatic amino acid that contributes to the hydrophobic character of peptides. This compound is typically white to off-white in appearance and is soluble in organic solvents, making it suitable for various chemical reactions. Its stability under standard laboratory conditions allows for its use in diverse applications, including drug development and the study of protein interactions. As with many chemical substances, proper handling and safety precautions are essential due to potential hazards associated with its use.
Formula:C22H25NO4
InChI:InChI=1S/C22H25NO4/c1-3-4-13-20(21(24)25)23(2)22(26)27-14-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,19-20H,3-4,13-14H2,1-2H3,(H,24,25)/t20-/m0/s1
InChI key:RZZXDYZWHUAOEK-FQEVSTJZSA-N
SMILES:CCCC[C@@H](C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Synonyms:
  • N-Alpha-Fmoc-N-Alpha-Methyl-L-Norleucine
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-L-2-Aminocaproic Acid
  • N-Alpha-(9-Fluorenylmethoxycarbonyl)-N-Alpha-Methyl-L-Norleucine
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-Alpha-Methyl-L-Norleucine
  • Fmoc-L-Mench[Ch3(Ch2)3]-Cooh
  • Fmoc-L-Menle-Oh
  • Fmoc-Menle-Oh
  • Fmoc-Meacpo(2)-Oh
  • Fmoc-N-Me-Nle-Oh
  • Fmoc-N-Me-L-Nle-OH
  • See more synonyms
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