CAS 112885-42-4: Mosapride citrate
Description:Mosapride citrate is a medication primarily used as a gastroprokinetic agent, which means it enhances gastrointestinal motility. It is often prescribed for the treatment of functional dyspepsia and gastroesophageal reflux disease (GERD). The substance acts as a selective serotonin 5-HT4 receptor agonist, promoting the release of acetylcholine in the gastrointestinal tract, thereby facilitating peristalsis and improving gastric emptying. Mosapride citrate is typically administered in its citrate salt form, which enhances its solubility and bioavailability. The compound is characterized by its relatively low toxicity and favorable safety profile, making it suitable for long-term use in patients with digestive disorders. In terms of physical properties, it is generally a white to off-white crystalline powder, soluble in water, and stable under normal storage conditions. Its pharmacokinetics involve rapid absorption and a moderate half-life, allowing for effective dosing regimens. Overall, Mosapride citrate is an important therapeutic agent in the management of gastrointestinal motility disorders.
Formula:C21H25ClFN3O3·C6H8O7
InChI:InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key:InChIKey=HUZTYZBFZKRPFG-UHFFFAOYSA-N
SMILES:O=C(O)CC(O)(C(=O)O)CC(=O)O.O=C(NCC1OCCN(CC2=CC=C(F)C=C2)C1)C3=CC(Cl)=C(N)C=C3OCC
- Synonyms:
- (+-)-4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)B
- 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
- 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate dihydrate (salt)
- As 4370
- As4370
- Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Benzamide,4-Amino-5-Chloro-2-Ethoxy-N-((4-((4-Fluorophenyl)Methyl)-2-Morpholin
- Enzamidecitrate
- Gasmotin
- Mosid MT
- See more synonyms
- Yl)Methyl)-,2-Hydroxy-1,2,3-Propanetricarboxylate(1:1)
- Mosapride citrate
