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Amifostine trihydrate

CAS 112901-68-5: Amifostine trihydrate

Description:Amifostine trihydrate, with the CAS number 112901-68-5, is a chemical compound primarily used as a cytoprotective agent in oncology. It is a prodrug that is converted in the body to its active form, which acts as a free radical scavenger, thereby protecting normal tissues from the harmful effects of chemotherapy and radiation therapy. The trihydrate form indicates that the compound contains three molecules of water, which can influence its solubility and stability. Amifostine is known for its ability to reduce the incidence of xerostomia (dry mouth) in patients undergoing head and neck radiation therapy. It is typically administered intravenously and has a relatively short half-life, necessitating careful timing in relation to chemotherapy or radiation treatments. The compound is characterized by its ability to donate thiol groups, which play a crucial role in its protective mechanisms. While generally well-tolerated, it can cause side effects such as hypotension and nausea, highlighting the importance of monitoring during administration.

Formula:C5H21N2O6PS

InChI:InChI=1/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2

  • Synonyms:
  • S-[2-(3-Aminopropyl)amino]ethyl]dihydrogen phosphorothioate,trihydrate
  • 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate
  • S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen phosphorothioate
  • Anifostine trihydrate
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Amifostine trihydrate

CAS:112901-68-5

Ref: AC-46310

1gTo inquire
250mgTo inquire
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Amifostine

CAS:112901-68-5

Ref: 45-1019406

150mg656.00 €
Estimated delivery in United States, on Friday 7 Mar 2025
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Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester),trihydrate

CAS:112901-68-5

Ref: IN-DA00HCG5

1g157.00 €
5g619.00 €
50mg56.00 €
100mg68.00 €
250mg117.00 €
Estimated delivery in United States, on Monday 10 Mar 2025
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S-(2-((3-Aminopropyl)Amino)Ethyl)O,O-DihydrogenPhosphorothioateTrihydrate

CAS:112901-68-5

Ref: 54-OR1014896

1g177.00 €
5g474.00 €
25g1,457.00 €
100mg62.00 €
250mg92.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Amifostine trihydrate

CAS:112901-68-5

Ref: 7W-GP7989

Undefined sizeTo inquire
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Amifostine trihydrate

CAS:112901-68-5

Ref: TM-T6381

5mg37.00 €
10mg56.00 €
25mg115.00 €
50mg167.00 €
100mg256.00 €
200mg410.00 €
500mg680.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Amifostine Trihydrate

Controlled Product
CAS:112901-68-5

Ref: TR-A576815

1g683.00 €
100mg155.00 €
2500mg1,306.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Amifostine trihydrate

CAS:112901-68-5

Ref: 10-F517636

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5gTo inquire
50mgTo inquire
100mgTo inquire
250mgTo inquire
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Amifostine trihydrate

CAS:112901-68-5

Ref: 3D-FA45620

100mg147.00 €
Estimated delivery in United States, on Wednesday 19 Mar 2025
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