CAS 112901-68-5: Amifostine trihydrate
Description:Amifostine trihydrate, with the CAS number 112901-68-5, is a chemical compound primarily used as a cytoprotective agent in oncology. It is a prodrug that is converted in the body to its active form, which acts as a free radical scavenger, thereby protecting normal tissues from the harmful effects of chemotherapy and radiation therapy. The trihydrate form indicates that the compound contains three molecules of water, which can influence its solubility and stability. Amifostine is known for its ability to reduce the incidence of xerostomia (dry mouth) in patients undergoing head and neck radiation therapy. It is typically administered intravenously and has a relatively short half-life, necessitating careful timing in relation to chemotherapy or radiation treatments. The compound is characterized by its ability to donate thiol groups, which play a crucial role in its protective mechanisms. While generally well-tolerated, it can cause side effects such as hypotension and nausea, highlighting the importance of monitoring during administration.
Formula:C5H21N2O6PS
InChI:InChI=1/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2
- Synonyms:
- S-[2-(3-Aminopropyl)amino]ethyl]dihydrogen phosphorothioate,trihydrate
- 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid trihydrate
- S-{2-[(3-aminopropyl)amino]ethyl} dihydrogen phosphorothioate
- Anifostine trihydrate

Amifostine trihydrate
Ref: AC-46310
1g | To inquire | ||
250mg | To inquire |

Amifostine
Ref: 45-1019406
150mg | 656.00 € |

Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrogen phosphate (ester),trihydrate
Ref: IN-DA00HCG5
1g | 157.00 € | ||
5g | 619.00 € | ||
50mg | 56.00 € | ||
100mg | 68.00 € | ||
250mg | 117.00 € |

S-(2-((3-Aminopropyl)Amino)Ethyl)O,O-DihydrogenPhosphorothioateTrihydrate
Ref: 54-OR1014896
1g | 177.00 € | ||
5g | 474.00 € | ||
25g | 1,457.00 € | ||
100mg | 62.00 € | ||
250mg | 92.00 € |

Ref: 7W-GP7989
Undefined size | To inquire |

Amifostine trihydrate
Ref: TM-T6381
5mg | 37.00 € | ||
10mg | 56.00 € | ||
25mg | 115.00 € | ||
50mg | 167.00 € | ||
100mg | 256.00 € | ||
200mg | 410.00 € | ||
500mg | 680.00 € |

Amifostine Trihydrate
Controlled ProductRef: TR-A576815
1g | 683.00 € | ||
100mg | 155.00 € | ||
2500mg | 1,306.00 € |

Amifostine trihydrate
Ref: 10-F517636
1g | To inquire | ||
5g | To inquire | ||
50mg | To inquire | ||
100mg | To inquire | ||
250mg | To inquire |

Amifostine trihydrate
Ref: 3D-FA45620
100mg | 147.00 € |