CAS 112984-60-8

6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)-Thiazeto(3,2-Alpha)Quinoline-3-Carboxylic Acid

Description:

6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)-Thiazeto(3,2-Alpha)Quinoline-3-Carboxylic Acid, with CAS number 112984-60-8, is a synthetic compound characterized by its complex heterocyclic structure, which includes a quinoline core fused with a thiazole ring. The presence of a fluorine atom at the 6-position and a piperazine moiety at the 7-position contributes to its unique pharmacological properties. This compound typically exhibits a range of biological activities, making it of interest in medicinal chemistry, particularly in the development of antimicrobial or antitumor agents. Its carboxylic acid functional group may enhance solubility and bioavailability, while the oxo group can participate in various chemical reactions. The compound's structural features suggest potential interactions with biological targets, which can be explored further in drug discovery research. Overall, this substance represents a class of compounds that may offer therapeutic benefits, although specific applications and efficacy would require detailed experimental investigation.

Formula: C₁₆H₁₆FN₃O₃S

InChI: InChI=1/C16H16FN3O3S/c1-8-20-11-7-12(19-4-2-18-3-5-19)10(17)6-9(11)14(21)13(16(22)23)15(20)24-8/h6-8,18H,2-5H2,1H3,(H,22,23)

InChI key: InChIKey=SUXQDLLXIBLQHW-UHFFFAOYSA-N

SMILES: CC1N2C=3C(C(=O)C(C(O)=O)=C2S1)=CC(F)=C(C3)N4CCNCC4

Synonyms:

• 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylic acid, 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-
• 1H,4H-[1,3]Thiazeto[3,2-a]quinoline-3-carboxylicacid,6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)
• 6-Fluoro-1-Methyl-4-OXO-7-(1-PIPRAZINYL)-4H-(1,3)-THIAZETO(3,2-A)quinoline-3-CAR
• 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)Thiazeto(3,2-A)Quinoline-3-Carboxylicacid
• 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3) -thiazeto (3,2-a)quinoline-3-carboxylic acid
• 6-Fluoro-1-methyl-4-oxo-7-piperazin-1-yl-4H-2-thia-8b-aza-cyclobuta[a] naphthalene-3-carboxylic acid
• 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-1H,4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
• 6-fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid
• Af 3013
• Nad 394
• Nm 394
• Pl-11
• Ulifloxacin
• Prulifloxacin Intermediate PL-11
• 6-Fluoro-1-methyl-7-(1-piperazinyl)-4-oxo-4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid
• 6-FLUORO-7-PIPERAZINE-1-METHYL-4-OXY-[1,3]THIOAZACYCLIC[3,2-A]-QUINOLINE-3-CARBOXYLIC ACID
• PRULIFLOXACIN INTERMEDIATE 3
• 6-Fluoro-1-Methyl-4-Oxo-7-(1-Piperazinyl)-4H-(1,3)-Thiazeto(3,2-Alpha)Quinoline-3-Carboxylic Acid
• 6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto
• 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)-thiazeto(3,2-a)quinoline-3-carboxylic acid cas:(intermediate of prulifloxacin)
• 6-FLUORO-1-METHYL-4-OXO-7-(1-PIPRAZINYL)-1H,4H-(1,3)THIAZETO(3,2-A)QUINOLINE-3-CARBOXYLIC ACID

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

CAS: 112984-60-8

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

Formula: C₁₆H₁₆FN₃O₃S

Purity: 95%

Molecular weight: 349.39

Ref: 54-PC1002301

Ulifloxacin

CAS: 112984-60-8

Formula: C₁₆H₁₆FN₃O₃S

Molecular weight: 349.39

Ref: 4Z-U-041

6-Fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid

CAS: 112984-60-8

Formula: C₁₆H₁₆FN₃O₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 349.3799

Ref: IN-DA0081N3

Ulifloxacin

CAS: 112984-60-8

6-Fluoro-1-methyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid

Formula: C₁₆H₁₆FN₃O₃S

Purity: 95%

Molecular weight: 349.38

Ref: IN-DG16344

Ulifloxacin

CAS: 112984-60-8

Extensive research has been conducted on the antimicrobial activity of 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)thiazeto(3,2a)quinoline-3-carboxylic acid (FPMT). FPMT is a levorotatory compound that is rapidly metabolized by esterases to 6FMT, which is also active against bacteria. FPMT inhibits bacterial growth, but does not inhibit mammalian cell growth. The main mechanism of action for FPMT is probably through its ability to inhibit the synthesis of bacterial DNA and RNA. This drug has been shown to be effective against sinusitis caused by bacterial rhinosinusitis and urinary tract infections caused by Escherichia coli and Pseudomonas aeruginosa. FPMT can be used as an alternative to prulifloxacin for the treatment of these types of infections

Formula: C₁₆H₁₆FN₃O₃S

Purity: Min. 98 Area-%

Molecular weight: 349.38 g/mol

Ref: 3D-FF44006

Ulifloxacin

CAS: 112984-60-8

Formula: C₁₆H₁₆FN₃O₃S

Molecular weight: 349.4

Ref: BE-RMCU004000

Ulifloxacin

CAS: 112984-60-8

Applications A metabolite of Prulifloxacin (P838885). Ulifloxacin is a new quinolone antibiotic and it is effective against pneumonia.
References Kim, D., et al.: J. Pharm. Sci., 77, 200 (1988), Suzuki, T., et al.: Drug Metab. Dispos., 30, 1393 (2002), Sun, J., et al.: Eur. J. Pharm. Biopharm., 64, 238 (2006),

Formula: C₁₆H₁₆FN₃O₃S

Color and Shape: Neat

Molecular weight: 349.38

Ref: TR-U700700

Prulifloxacin Impurity 1

CAS: 112984-60-8

Formula: C₁₆H₁₆FN₃O₃S

Molecular weight: 349.38

Ref: ST-EA-CP-P202001