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CAS 113-52-0

:

Imipramine HCl

Description:
Imipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby increasing their availability in the synaptic cleft. This mechanism contributes to its antidepressant effects. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Imipramine hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dry mouth, sedation, weight gain, and potential cardiovascular effects, necessitating careful monitoring, especially in patients with pre-existing conditions. Due to its pharmacological profile, it is classified as a prescription medication and should be used under medical supervision. Additionally, it is important to consider potential interactions with other medications, as well as the risk of withdrawal symptoms upon discontinuation. Overall, Imipramine hydrochloride remains a significant option in the pharmacotherapy of depression and related disorders.
Formula:C19H25ClN2
InChI:InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H
InChI key:InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
  • 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
  • 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
  • Apo-Imipramine
  • Censtim
  • Censtin
  • See more synonyms
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