CAS 113-53-1
:dosulepin
Description:
Dosulepin, also known as dothiepin, is a tricyclic antidepressant primarily used in the treatment of depression and anxiety disorders. Its chemical structure features a dibenzocycloheptene core, which contributes to its pharmacological properties. Dosulepin acts by inhibiting the reuptake of neurotransmitters, particularly serotonin and norepinephrine, thereby enhancing mood and alleviating depressive symptoms. The substance is typically administered in oral form and is known for its sedative effects, making it beneficial for patients with insomnia related to depression. However, it can also cause side effects, including dry mouth, dizziness, and weight gain. Due to its potential for toxicity in overdose situations, careful monitoring is essential when prescribing dosulepin. It is classified under the category of prescription medications and should be used under medical supervision. As with many antidepressants, the therapeutic effects may take several weeks to manifest, and discontinuation should be managed to avoid withdrawal symptoms. Overall, dosulepin remains a relevant option in the pharmacotherapy of mood disorders.
Formula:C19H21NS
InChI:InChI=1/C19H21NS/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11-
InChI key:InChIKey=PHTUQLWOUWZIMZ-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(CSC=3C1=CC=CC3)=CC=CC2
Synonyms:- 1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-
- 3-(6,11-Dihydrodibenzo(B,E)Thiepin-11-Ylidene)Propyldimethylamine
- 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine
- Dibenzo[b,e]thiepin, 1-propanamine deriv.
- Dibenzo[b,e]thiepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine, N,N-dimethyl-
- Dosulepine
- Dothep
- Dothiepin
- Iz 914
- Prothiaden
- Prothiadene
- Dibenzo[b,e]thiepin-Δ11(6H),γ-propylamine, N,N-dimethyl-
- Dosulepin
- Propylamine, N,N-dimethyl-3-(dibenzo(b,e)thiepin-delta-sup(11(6H),gamma))-
- (3E)-3-Dibenzo[b,E]thiepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine
- Dothiepin-d3 Maleate
- n,n-dimethyl-3-(dibenzo(b,e)thiepin-delta-sup(11(6h),gamma))-propylamin
- Dolsulepine
- Prothiaden spofa
- iz914
- 3-Dibenzo[b,e]thiepin-11(6H)-ylidine-N,N-dimethyl-propanamine
- 3-dibenzo(b,e)thiepin-11(6h)-ylidene-n,n-dimethyl-1-propanamin
- DOTHIEPIN,3-DIBENZO[B,E] THIEPIN-11-(6H)-YLIDENE-N,N-DIMETHYL-PROPONAMINE
- 3-DIBENZO[B,E] THIEPIN-11-(6H)-YLIDENE-N,N-DIMETHYL-PROPONAMINE
- Methiaden
- N,N-Dimethyldibenzo(b,e)thiepin-delta-sup(11(6H),gamma)propylamine
- Dothiepin (cis/trans)
- CIS,TRANS-DOTHIEPIN,1.0MG/MLINMETHANOL
- (E)-3-[Dibenzo[b,e]thiepin-11(6H)-ylidene]-N,N-dimethylpropane-1-amine
- (E)-3-[Dibenzo[b,e]thiepin-11(6H)-ylidene]-N,N-dimethyl-1-propanamine
- N,N-Dimethyl- dibenzo[b,e]thiepin-11(6H),-propylamine
- 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-diMethyl-
- 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin
- Dibenzo[b,e]thiepin-delta11(6H),gamma-propylamine, N,N-dimethyl-
- See more synonyms
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Found 7 products.
Dothiepin
CAS:Controlled ProductApplications A tricyclic antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Metysova, J., et al.: Arzneim.-Forsch., 13, 1039 (1963), Maguire, K.P., et al.: Br. J. Clin. Pharmacol., 12, 405 (1981), Donovan, S., et al.: Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 18, 1143 (1994),Formula:C19H21NSColor and Shape:NeatMolecular weight:295.44Dothiepin
CAS:Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancingFormula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.44
