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CAS 1132748-21-0

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MYCOPHENOLATE MOFETIL-D4

Description:
Mycophenolate mofetil-D4 is a deuterated form of mycophenolate mofetil, which is an immunosuppressive agent primarily used in organ transplantation and autoimmune diseases. The deuterated version, indicated by the "D4," contains four deuterium atoms, which are isotopes of hydrogen, enhancing its stability and allowing for more precise tracking in pharmacokinetic studies. Mycophenolate mofetil itself works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH), leading to a reduction in purine synthesis and subsequently suppressing lymphocyte proliferation. This action is crucial in preventing organ rejection in transplant patients. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other immunosuppressants. Its chemical structure includes a morpholinoethyl group and a phenolic moiety, contributing to its solubility and bioavailability. As a research tool, mycophenolate mofetil-D4 is valuable for studying drug metabolism and pharmacodynamics due to its isotopic labeling, which aids in distinguishing it from non-deuterated forms in biological samples.
Formula:C23H27D4NO7
Synonyms:
  • Mycophenolic Acid-d4-2-(4-Morpholinyl)ethyl Ester
  • (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-hexenoic Acid-d4 4-methyl-2-(4-morpholinyl)ethyl Ester
  • Mycophenolic Acid-2-(4-Morpholinyl)ethyl-d4 Ester
  • TM-MMF-d4
  • MYCOPHENOLATE MOFETIL-D4
  • RS 61443-d4
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