CAS 1134-47-0

Baclofen

Description:

Baclofen is a pharmaceutical compound primarily used as a muscle relaxant and antispastic agent. It is classified as a gamma-aminobutyric acid (GABA) derivative, functioning as a GABA_B receptor agonist, which helps to inhibit excessive neuronal activity. This mechanism makes it effective in treating conditions such as multiple sclerosis and spinal cord injuries, where muscle spasticity is prevalent. Baclofen is typically administered orally or via intrathecal delivery for severe cases. The substance is characterized by its white to off-white crystalline powder form, with a relatively low solubility in water, which can influence its bioavailability. Its molecular formula is C10H12ClNO2, and it has a moderate molecular weight. Baclofen's pharmacokinetics involve absorption in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. Side effects may include drowsiness, dizziness, and potential withdrawal symptoms if discontinued abruptly. Overall, Baclofen is a vital medication in managing spasticity, with a well-established profile in clinical use.

Formula:C₁₀H₁₂ClNO₂

InChI:InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)

InChI key:InChIKey=KPYSYYIEGFHWSV-UHFFFAOYSA-N

SMILES:C(CC(O)=O)(CN)C1=CC=C(Cl)C=C1

Synonyms:

(+/-)-beta(Aminomethyl)-4-chlorobenzenepropanoic acid, Lioresal
(3S)-4-amino-3-(4-chlorophenyl)butanoic acid
4-Amino-3-(4-Chlorophenyl)Butanoic Acid
4-Amino-3-(4-Chlorophenyl)Butyric Acid
4-Amino-3-(p-chlorophenyl)butyric acid
<span class="text-smallcaps">D</smallcap><smallcap>L</span>-4-Amino-3-p-chlorophenylbutanoic acid
<span class="text-smallcaps">D</smallcap><smallcap>L</span>-Baclofen
Atrofen
Ba 34647
Baclofene
Baclofeno
Baclon
Benzenepropanoic acid, β-(aminomethyl)-4-chloro-
Beta-(4-Chlorophenyl)-Gamma-Aminobutyric Acid
Beta-(4-Chlorophenyl)Gaba
Beta-(Aminomethyl)-4-Chlorobenzenepropanoic Acid
Beta-(Aminomethyl)-P-Chlorohydrocinnamic Acid
C 34647Ba
CIBA Ba 34647
Ciba 34,647-Ba
DL-4-Amino-3-p-chlorophenylbutanoic acid
Gamma-Amino-Beta-(P-Chlorophenyl)Butyric Acid
Hydrocinnamic acid, β-(aminomethyl)-p-chloro-
Lioresal
dl-Baclofen
β-(4-Chlorophenyl)-γ-aminobutyric acid
β-(Aminomethyl)-4-chlorobenzenepropanoic acid
β-(Aminomethyl)-p-chlorohydrocinnamic acid
β-(p-Chlorophenyl)-γ-aminobutyric acid
See more synonyms

Purity (%)

100

Found 25 products.

+ Info
Baclofen
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Purity:>98.0%(T)
Color and Shape:White to Light yellow to Light orange powder to crystal
Molecular weight:213.66
Ref: 3B-B3343
1g
33.00€
VAT not included
5g
82.00€
VAT not included
25g
244.00€
VAT not included
+ Info
(+/-)-Baclofen, 99+%
CAS:
- 1134-47-0
Selective GABA-b receptor agonist
Formula:C₁₀H₁₂ClNO₂
Purity:99+%
Molecular weight:213.66
Ref: 02-J62768
1g
87.00€
VAT not included
+ Info
Baclofen, 1mg/ml in Acetonitrile/Water : 1/1
CAS:
- 1134-47-0
Color and Shape:Single Solution
Ref: LP-BCL-1653-1LAH
1ml
150.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Color and Shape:Neat
Ref: 61-FOR1235.00
10mg
306.00€
VAT not included
+ Info
Baclofen 0.5 mg/ml in Methanol
CAS:
- 1134-47-0
Color and Shape:Single Solution
Ref: 61-AMP1235.00-08
1ml
188.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Color and Shape:Neat
Ref: LP-BCL-1653-10
10mg
188.00€
VAT not included
50mg
605.00€
VAT not included
100mg
1,085.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Baclofen
Formula:C₁₀H₁₂CINO₂
Purity:99.6%
Color and Shape:Off White
Molecular weight:316.99128
Ref: 47-28
150mg
242.00€
VAT not included
+ Info
BACLOFEN CRS
CAS:
- 1134-47-0
BACLOFEN CRS
Formula:C₁₀H₁₂ClNO₂
Molecular weight:213.6608
Ref: 41-B0200000
130mg
132.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Aromatic amino-acids and their esters,other than those containing more than one kind of oxygen function for use as drugs
Formula:C₁₀H₁₂ClNO₂
Color and Shape:White Powder
Molecular weight:213.05566
Ref: 45-1048200
+ Info
Baclofen
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:213.6608
Ref: IN-DA003NYH
1g
25.00€
VAT not included
5g
34.00€
VAT not included
10g
53.00€
VAT not included
25g
67.00€
VAT not included
100g
153.00€
VAT not included
1kg
562.00€
VAT not included
5kg
1,851.00€
VAT not included
10kg
3,465.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.
Formula:C₁₀H₁₂ClNO₂
Purity:98% - 99.94%
Color and Shape:White Solid
Molecular weight:213.66
Ref: TM-T1065
200mg
34.00€
VAT not included
500mg
52.00€
VAT not included
1g
63.00€
VAT not included
5g
213.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Baclofen
Formula:C₁₀H₁₂ClNO₂
Purity:≥98%
Molecular weight:213.66
Ref: 54-BUP17874
200mg
55.00€
VAT not included
500mg
74.00€
VAT not included
1g
96.00€
VAT not included
5g
326.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Molecular weight:213.66
Ref: 4Z-B-4025
5mg
To inquire
100mg
To inquire
10mg
343.00€
VAT not included
25mg
436.00€
VAT not included
50mg
623.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Molecular weight:213.66
Ref: 7W-GP4566
ne
To inquire
+ Info
Baclofen
CAS:
- 1134-47-0
Baclofen
Formula:C₁₀H₁₂ClNO₂
Purity:98%
Molecular weight:213.66
Ref: 54-OR1029079
5g
30.00€
VAT not included
25g
87.00€
VAT not included
100g
296.00€
VAT not included
500g
973.00€
VAT not included
+ Info
Baclofen
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Color and Shape:Neat
Molecular weight:213.66
Ref: 04-C10418050
250mg
88.00€
VAT not included
+ Info
Baclofen
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Color and Shape:Neat
Molecular weight:213.66
Ref: 86-MM1235.00
250mg
307.00€
VAT not included
+ Info
Baclofen
CAS:
- 1134-47-0
Formula:C₁₀H₁₂ClNO₂
Molecular weight:213.66
Ref: ST-EA-CP-B3000
10mg
To inquire
25mg
To inquire
50mg
To inquire
100mg
To inquire
+ Info
Dibaclofen Urea Dicyclohexylammonium Salt
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Applications Dibaclofen Urea Dicyclohexylammonium Salt, is an impurity of Baclofen (B108000), which is an specific GABA-B receptor agonist, and muscle relaxant (skeletal). It is primarily used to treat spasticity.
References Ahuja, S., et al.: Anal. Profiles Drug Subs., 14, 527 (1985), Brogden, R.N., et al.: Drugs, 8,1 (1974)
Formula:C₂₁H₂₀Cl₂N₂O₅·2C₁₂H₂₄N
Color and Shape:Neat
Molecular weight:815.951
Ref: TR-D417365
50mg
263.00€
VAT not included
250mg
1,061.00€
VAT not included
500mg
1,692.00€
VAT not included
+ Info
Baclofen
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Applications Specific GABA-B receptor agonist. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ahuja, S., et al.: Anal. Profiles Drug Subs., 14, 527 (1985); Brogden, R.N., et al.: Drugs, 8,1 (1974);
Formula:C₁₀H₁₂ClNO₂
Color and Shape:Neat
Molecular weight:213.66
Ref: TR-B108000
500mg
88.00€
VAT not included
1g
127.00€
VAT not included
5g
215.00€
VAT not included
+ Info
Baclofen
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
GABA(B) agonist; anti-spastic agent; skeletal muscle relaxant
Formula:C₁₀H₁₂ClNO₂
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:213.66 g/mol
Ref: 3D-FB18127
25g
376.00€
VAT not included
50g
612.00€
VAT not included
+ Info
Baclofen - Bio-X ™
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Baclofen is a GABA-ergic agonist drug that is used to manage severe spasticity of the cerebral and spinal origin in patients. The exact action of this drug is unclear however it is said that Baclofen inhibits the transmission of both mono- and polysynaptic reflexes at the spinal cord, relaxing spasticity.
Formula:C₁₀H₁₂ClNO₂
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:213.66 g/mol
Ref: 3D-BB166152
10mg
186.00€
VAT not included
+ Info
(+/-)-Baclofen
CAS:
- 1134-47-0
M01382 - (+/-)-Baclofen
Formula:C₁₀H₁₂ClNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:213.66
Ref: 10-M01382
1g
18.00€
VAT not included
500mg
18.00€
VAT not included
5g
29.00€
VAT not included
10g
41.00€
VAT not included
25g
72.00€
VAT not included
100g
179.00€
VAT not included
+ Info
Baclofen-d4,15N
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 1134-47-0
Formula:C₁₀H₈D₄ClNO₂
Color and Shape:Neat
Molecular weight:382.454
Ref: TR-B108001
25mg
5,142.00€
VAT not included
+ Info
Baclofen RS
CAS:
- 1134-47-0
Color and Shape:White To Pale Yellowish White Solid Crystalline Powder
Ref: 2K-1112000021
800mg
Discontinued
Request information
Discontinued product