CAS 1134639-23-8

Di-(tert-Butyl-dimethylsilyl) Curcumin-d6

Controlled Product

CAS: 1134639-23-8

Formula: C₃₃D₆H₄₂O₆Si₂

Color and Shape: Neat

Molecular weight: 602.939

Ref: TR-D428052

Di-(tert-Butyl-dimethylsilyl) Curcumin

Controlled Product

CAS: 1134639-23-8

Applications Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
References Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007),

Formula: C₃₃H₄₈O₆Si₂

Color and Shape: Neat

Molecular weight: 596.9

Ref: TR-D428050

Di-(tert-butyl-dimethylsilyl) curcumin

CAS: 1134639-23-8

Di-(tert-butyl-dimethylsilyl) curcumin is a research tool that is used in the study of cell biology, pharmacology, and ion channels. It is an inhibitor of ligand or receptor interactions. Di-(tert-butyl-dimethylsilyl) curcumin has been shown to have a high purity and is suitable for use in life science experiments. This chemical is also an activator of ion channels and has been used as a reagent to study protein interactions.

Formula: C₃₃H₄₈O₆Si₂

Purity: Min. 95%

Molecular weight: 596.9 g/mol

Ref: 3D-JVB63923