CAS 1135243-19-4

N-{3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl}-2,1,3-benzothiadiazole-4-sulfonamide

Description:

N-{3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl}-2,1,3-benzothiadiazole-4-sulfonamide is a chemical compound characterized by its complex structure, which includes a benzothiadiazole moiety, a sulfonamide group, and a piperazine derivative. This compound typically exhibits properties such as solubility in polar solvents, which is influenced by the presence of the sulfonamide group. Its molecular structure suggests potential biological activity, particularly in medicinal chemistry, where such compounds may serve as pharmacological agents. The presence of the pyridine and piperazine rings may contribute to its ability to interact with biological targets, making it a candidate for further research in drug development. Additionally, the compound's functional groups may impart specific reactivity and stability characteristics, which are essential for its application in various chemical and biological contexts. Overall, this compound represents a class of sulfonamide derivatives that are of interest for their potential therapeutic uses and chemical reactivity.

Formula: C₁₈H₂₀N₆O₃S₂

InChI: InChI=1S/C18H20N6O3S2/c25-17(24-12-10-23(11-13-24)14-4-7-19-8-5-14)6-9-20-29(26,27)16-3-1-2-15-18(16)22-28-21-15/h1-5,7-8,20H,6,9-13H2

InChI key: WXDHQWPQLKGANZ-UHFFFAOYSA-N

SMILES: c1cc2c(c(c1)S(=O)(=O)NCCC(=O)N1CCN(CC1)c1ccncc1)nsn2

Synonyms:

• N-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonaMide
• N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide hydrate
• CID24768606
• VU0255035 hydrate
• 2,1,3-Benzothiadiazole-4-sulfonamide, N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-
• VU 0255035
• N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
• ML012
• N-{3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl}-2,1,3-benz...
• N-(3-oxo-3-(4-(pyridine-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide hydrate

2,1,3-Benzothiadiazole-4-sulfonamide, N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-

CAS: 1135243-19-4

Formula: C₁₈H₂₀N₆O₃S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 432.5198

Ref: IN-DA0008W7

N-[3-Oxo-3-[4-(4-Pyridinyl)-1-Piperazinyl]Propyl]-2,1,3-Benzothiadiazole-4-Sulfonamide

CAS: 1135243-19-4

N-[3-Oxo-3-[4-(4-Pyridinyl)-1-Piperazinyl]Propyl]-2,1,3-Benzothiadiazole-4-Sulfonamide

Formula: C₁₈H₂₀N₆O₃S₂

Purity: 95%

Molecular weight: 432.52

Ref: 54-OR1025323

VU 0255035

CAS: 1135243-19-4

VU 0255035

Formula: C₁₈H₂₀N₆O₃S₂

Purity: ≥95%

Molecular weight: 432.52

Ref: 54-BUP11596

VU0255035

CAS: 1135243-19-4

N-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide

Formula: C₁₈H₂₀N₆O₃S₂

Purity: 95%

Molecular weight: 432.52

Ref: IN-DG291918

2,1,3-Benzothiadiazole-4-sulfonamide, N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-

CAS: 1135243-19-4

Purity: 95%

Molecular weight: 432.519989

Ref: 10-F865527

VU 0255035

CAS: 1135243-19-4

VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.

Formula: C₁₈H₂₀N₆O₃S₂

Purity: 98.09% - 98.1%

Color and Shape: Yellow Solid

Molecular weight: 432.52

Ref: TM-T23508

VU 0255035

CAS: 1135243-19-4

VU0255035 is a drug that blocks the muscarinic acetylcholine receptor, which is used to treat diabetic neuropathy. The development of VU0255035 was based on the identification of a monoclonal antibody that selectively binds to the M1 muscarinic acetylcholine receptor and blocks its activity. VU0255035 has been shown to inhibit locomotor activity in animals, which may be due to its ability to inhibit acetylcholine release from cholinergic nerve endings. This drug also inhibits the production of inflammatory molecules such as nitric oxide and prostaglandin E2 in animal models. VU0255035 has also been shown to be effective in treating autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and psoriasis. In addition, it may have potential for cancer therapy as it has been shown to inhibit tumor growth and induce apoptosis in various cancer cell lines.

Formula: C₁₈H₂₀N₆O₃S₂

Purity: Min. 95%

Molecular weight: 432.52 g/mol

Ref: 3D-KVB24319