CAS 1135280-28-2

KN92 phosphate

Description:

KN92 phosphate, with the CAS number 1135280-28-2, is a chemical compound that is primarily recognized as a selective inhibitor of certain protein kinases, particularly calcium/calmodulin-dependent protein kinase II (CaMKII). This compound is often utilized in biochemical research to study the role of CaMKII in various cellular processes, including signal transduction, muscle contraction, and neuronal function. KN92 phosphate is characterized by its ability to modulate calcium signaling pathways, making it a valuable tool in pharmacological studies. The compound is typically soluble in organic solvents and may exhibit varying stability depending on environmental conditions. Its specificity and potency make it an important reagent in the exploration of kinase-related pathways and their implications in diseases such as cancer and neurodegenerative disorders. As with many chemical substances, proper handling and safety precautions are essential when working with KN92 phosphate in laboratory settings.

Formula: C₂₄H₂₈ClN₂O₇PS

InChI: InChI=1S/C24H25ClN2O3S.H3O4P/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23;1-5(2,3)4/h3-16,26H,17-18H2,1-2H3;(H3,1,2,3,4)/b6-5+;

InChI key: XRQHWVVDNMJDEQ-IPZCTEOASA-N

SMILES: CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O

Synonyms:

• KN 92 phosphate
• KN92 phosphate
• CS-1093
• KN 92; KN92
• KN-92 (phosphate)
• KN92-H3PO4

N-(2-(((3-(4-Chlorophenyl)Allyl)(Methyl)Amino)Methyl)Phenyl)-4-Methoxybenzenesulfonamide Phosphate

CAS: 1135280-28-2

N-(2-(((3-(4-Chlorophenyl)Allyl)(Methyl)Amino)Methyl)Phenyl)-4-Methoxybenzenesulfonamide Phosphate

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: 98%

Molecular weight: 554.98

Ref: 54-OR1024287

KN-92 phosphate

CAS: 1135280-28-2

KN-92 phosphate

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: ≥98%

Molecular weight: 554.98

Ref: 54-BUP10072

N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-4-methoxybenzenesulfonamide; phosphoric acid

CAS: 1135280-28-2

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: 98%

Color and Shape: Liquid

Molecular weight: 554.9801

Ref: IN-DA008TH6

KN-92 phosphate

CAS: 1135280-28-2

KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 554.98

Ref: TM-T4530

KN-92

CAS: 1135280-28-2

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 554.98

Ref: 7W-GX2819

KN-92 phosphate

CAS: 1135280-28-2

N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide phosphate

Formula: C₂₄H₂₈ClN₂O₇PS

Purity: 98%

Molecular weight: 554.98

Ref: IN-DG447511

KN 92

Controlled Product

CAS: 1135280-28-2

KN 92 is an inhibitor of phosphodiesterase 3 that has been shown to reduce intracellular Ca2+ levels, inhibit neuronal death and preserve mitochondrial membrane potential. KN 92 also prevents the development of structural heart disease in rats, which may be due to its ability to maintain normal cardiac function and a reduction in the overload of Ca2+. KN 92 improves cardiac output by increasing dopamine levels in the atria and ventricles, which increases heart rate. This drug can cause side effects such as nausea, vomiting, diarrhea, headache, fatigue and dizziness.

Formula: C₂₄H₂₅ClN₂O₃S·H₃PO₄

Purity: Min. 95%

Molecular weight: 554.98 g/mol

Ref: 3D-KVB28028