CymitQuimica logo

CAS 113665-84-2

:

Clopidogrel

Description:
Clopidogrel is an antiplatelet medication primarily used to prevent blood clots in patients with cardiovascular diseases, such as those who have experienced a heart attack or stroke. It functions as a prodrug, meaning it requires metabolic activation to exert its therapeutic effects. Clopidogrel selectively inhibits the P2Y12 adenosine diphosphate (ADP) receptor on platelets, thereby preventing platelet aggregation. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract, although its bioavailability is affected by first-pass metabolism. Clopidogrel is characterized by its relatively low solubility in water and is often formulated as a bisulfate salt to enhance its stability and absorption. The drug has a half-life of approximately 8 hours, but its antiplatelet effects can last for several days due to irreversible binding to the P2Y12 receptor. Common side effects may include bleeding complications, gastrointestinal disturbances, and, in rare cases, hypersensitivity reactions. Overall, Clopidogrel plays a crucial role in the management of thrombotic disorders.
Formula:C16H16ClNO2S
InChI:InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1
InChI key:InChIKey=GKTWGGQPFAXNFI-HNNXBMFYSA-N
SMILES:[C@H](C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3
Synonyms:
  • Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-
  • Clopidogrel
  • Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-
  • (S)-Methyl α-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-α-(o-chlorophenyl)acetate
  • (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.