CAS 114-07-8

Erythromycin

Description:

Erythromycin is a macrolide antibiotic that is primarily used to treat bacterial infections. It is derived from the bacterium Saccharopolyspora erythraea and is effective against a variety of Gram-positive bacteria and some Gram-negative bacteria. The chemical structure of erythromycin features a large lactone ring, which is characteristic of macrolides, along with several sugar moieties that contribute to its solubility and biological activity. Erythromycin works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. It is commonly used in treating respiratory tract infections, skin infections, and certain sexually transmitted infections. Erythromycin is available in various formulations, including oral tablets, topical ointments, and intravenous preparations. While generally well-tolerated, it can cause side effects such as gastrointestinal disturbances and may interact with other medications due to its effects on liver enzymes. Resistance to erythromycin has been observed in some bacterial strains, which can limit its effectiveness in certain infections.

Formula: C₃₇H₆₇NO₁₃

InChI: InChI=1/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21?,22-,23+,24+,25-,26+,28-,29?,30?,31+,32?,34?,35-,36-,37-/m1/s1

InChI key: InChIKey=ULGZDMOVFRHVEP-RWJQBGPGSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Synonyms:

• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• (3R,7R,9R,11R,13S,14R)-6-{[(3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• 6-{[4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name)
• Abboticin
• Abomacetin
• Ak-Mycin
• Aknin
• Dotycin
• Drmysin
• E-Base
• E-mycin
• E.E.S
• EMU
• Emgel
• Ergel
• Eritocina
• Eritrex
• Eritrocina
• Eritromed
• Eritromicina
• Ermycin
• Erthrogran
• Ery Derm
• Ery-Ped
• Ery-Tab
• EryDerm
• Eryacne
• Eryc
• Erycen
• Erycette
• Erycin
• Erycinum
• Erygel
• Erymax
• Erytab
• Erythro
• Erythrocin
• Erythrogran
• Erythroguent
• Erythromast
• Erythromast 36
• Erythromid
• Erythromycin A
• Erythromycine
• Ilocap
• Ilosone
• Ilotycin
• Inderm
• L-alpha-Egg-phosphatidylcholine
• Nsc 55929
• Oxacyclotetradecane, erythromycin deriv.
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• Oxacyclotetradecane-2,10-dione, 4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-
• P.C.E.
• PCE
• Pantomicina
• Pediamycin
• Retcin
• Robimycin
• Statcin
• Staticin
• Stiemycin
• T-Stat
• Theramycin Z
• Torlamicina
• Torlamicna
• Vetwic
• Wintrocin
• Wyamycin-s
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
• Erythromycin
• ErMysin
• ERYTHROMYCIN STANDARD SOLUTION*
• ERYTHROMYCIN BASE
• ERYTHROMYCIN USP(CRM STANDARD)
• Abomacetin AK-Mycin, Aknin
• Erythromycin,Erythromycinum
• StreptoMyces erythreus
• ERYTHROMYCIN, PH EUR
• em
• ibo-hexopyranosyl)-oxy)-14-ethyl-7,12,13-tr///
• BRAND? volumetric flask BLAUBRAND? USP conformity certified
• (3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)-4-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)oxacyclotetradecane-2,10-dione
• propiocine
• nosyl)-oxy)-6,11,12,13-tetrahydroxy-2,4,6,8///
• Radix Ophiopogonis P.E.
• ERYTHROMYCIN C USP(CRM STANDARD)
• ERYTHROMYCIN.BASERESEARCH GRADE
• ERYTHROMYCIN THICYANATE
• (-)-Erythromycin, Eur.Pharm.
• erythromycin,compdwithmonododecylsulfate,sodiumsalt
• ERYTHROMYCIN WHO(CRM STANDARD)
• ERYTHROMYCIN CELL CULTURE TESTED
• (3R,5R,6S,7R,8R,11R,13R,14R,15S,16R)-7-((2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-16-ethyl-8,14,15-trihydroxy-5-((2R,4S,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yloxy)-3,6,8,11,13,15-hexamethyloxacyclohexadecane-2,12-dione
• ERYTHROMYCIN B USP(CRM STANDARD)
• pentadecanoicacid,3-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha-l-ribo-hexopyra
• ERYTHROMYCIN, BIOTECHNOLOGY PERFORMANCE
• sulfuricacid,monododecylester,sodiumsalt,compdwitherythromycin
• USP
• ERYTHROMYCIN MIXTURE A,B,C
• BRAND? USP BLAUBRAND? class AS graduated pipette
• ERYTHROMYCIN A EPE(CRM STANDARD)
• BRAND? USP BLAUBRAND? volumetric pipettes, one-mark
• BRAND? USP BLAUBRAND? class A measuring cylinder, tall form
• oxacyclotetradecane-2,10-dione,4-((2,6-dideoxy-3-c-methyl-3-o-methyl-alpha-l-r
• ERYTHROMYCIN 960 I.U./MG EPE(CRM STANDARD)
• BRAND? volumetric flask, USP, BLAUBRAND
• ERYTHROMYCIN PLANT CELL CULTURE TESTED
• Aknemycin
• ErythromycinAlkali
• ERYTHROMYCINUM
• Erythromycin (250 mg)
• ERYTHROMYCIN C*) EPE(CRM STANDARD)
• Erythromycin BasePhosphate & Salts
• ERYTHROMYCIN (90-95% ERYTHROMYCIN A)
• Bulb pipettes
• Erytromycin A
• Erithromycin
• Ilotycin, ErythroMycin
• BRAND? volumetric flask BLAUBRAND? USP 27 conformity certified
• ERYTHROMYCIN,POWDER,USP
• ERYTHROMYCIN C WHO(CRM STANDARD)
• (-)-Erythromycin,98%
• ERYTHROMYCIN, STREPTOMYCES ERYTHREUS
• knin
• ERYTHROMYCIN CELL CULTURE REAGENT
• Erythromycin (base and/or unspecified salts)
• ErythroMycin COS/CGMP
• nci-c55674
• erythromast36
• ERYTHROMYCIN A,B,C
• ERYTHROMYCIN 98%
• ERYTHROMYCIN USP
• erythromycinsodiumlaurylsulfate
• ERYTHROMYCIN 9-OXIME 90+% HPLC
• Erythromycin,E-Mycin, Erythrocin
• BRAND? volumetric flask BLAUBRAND? USP
• ERYTHROMYCIN RELATED COMPOUND NN-DEMETHYLERYTHROMYCIN A USP(CRM STANDARD)
• ERYTHROMYCIN B EPE(CRM STANDARD)
• Erythromycin (mixture of A,B,C)
• Erythromycin-Bp/Ep/Usp

Erythromycin-d3

Controlled Product

CAS: 114-07-8

Applications Isotope labelled Erythromycin (E649950), an antibiotic useful for the treatment of a number of bacterial infection, usually prescribed to patients with allergy to penicillin.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formula: C₃₇H₆₄D₃NO₁₃

Color and Shape: Neat

Molecular weight: 736.96

Ref: TR-E649954

Erythromycin

CAS: 114-07-8

Applications Erythromycin is an antibiotic.This compound is a contaminant of emerging concern (CECs).
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

Formula: C₃₇H₆₇NO₁₃

Color and Shape: White

Molecular weight: 733.93

Ref: TR-E649950

Erythromycin, Antibiotic for Culture Media Use Only

CAS: 114-07-8

Erythromycin, Antibiotic for Culture Media Use Only, is a macrolide antibiotic derived from the bacterium *Saccharopolyspora erythraea*. It functions by inhibiting protein synthesis, specifically targeting the 50S ribosomal subunit in susceptible bacteria. This action results in the prevention of peptide chain elongation, effectively halting bacterial growth and proliferation.

Formula: C₃₇H₆₇NO₁₃

Purity: Min. 93.0 Area-%

Molecular weight: 733.93 g/mol

Ref: 3D-E-3250

Erythromycin

CAS: 114-07-8

A broad-spectrum antibiotic of macrolide class, which targets 50S ribosomal subunit and inhibits protein synthesis. Erythromycin is widely used in molecular biology and biotechnology as a selection marker. Erythromycin is also an agonist of the motilin receptor, and it has prokinetic activity on the gut.

Formula: C₃₇H₆₇NO₁₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 733.93 g/mol

Ref: 3D-AE22796

Erythromycin for tissue culture

CAS: 114-07-8

Formula: C₃₇H₆₇NO₁₃

Color and Shape: White to off - white, Hygroscopic powder, Clear, Colourless

Molecular weight: 733.93

Ref: SR-48535

Erythromycin A

CAS: 114-07-8

Erythromycin A

Formula: C₃₇H₆₇NO₁₃

Purity: 96.7%

Color and Shape: White

Molecular weight: 733.46124

Ref: 47-794