CAS 114-86-3: Phenformin

Description: Phenformin is a biguanide derivative, primarily recognized for its role as an antihyperglycemic agent in the management of type 2 diabetes mellitus. It is characterized by its ability to decrease hepatic glucose production and enhance insulin sensitivity, thereby improving glucose uptake in peripheral tissues. Phenformin is known for its lipophilic nature, which allows it to penetrate cell membranes effectively. The compound has a relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. It is also associated with a risk of lactic acidosis, a serious side effect that has led to its withdrawal from the market in many countries. In terms of chemical structure, Phenformin features a biguanide backbone, which is essential for its biological activity. Its molecular formula reflects its composition of carbon, hydrogen, nitrogen, and oxygen atoms. Overall, while Phenformin has demonstrated efficacy in glycemic control, its safety profile has limited its clinical use in favor of other antidiabetic medications.

Formula: C₁₀H₁₅N₅

InChI: InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15)

InChI key: InChIKey=ICFJFFQQTFMIBG-UHFFFAOYSA-N

SMILES: N=C(N)NC(=N)NCCC=1C=CC=CC1

Synonyms:

• (Phenylethyl)biguanide
• 1-(Diaminomethylidene)-2-(2-phenylethyl)guanidine
• 1-Carbamimidamido-N-(2-phenylethyl)methanimidamide
• 1-Phenethylbiguanide
• Biguanide, 1-phenethyl-
• Cronoformin
• DB Comb.
• DB-retard
• DBI
• Debeone
• Diabis
• Dibiraf
• Dibotin
• Fenfoduron
• Fenformin
• Fenformina
• Fenormin
• Glukopostin
• Glyphen
• N-(2-Phenylethyl)imidodicarbonimidic diamide
• N-(β-Phenethyl)diguanide
• N-(β-phenethyl) biguanide
• Pedg
• Phenethylbiguanide
• Phenformin
• Phenformine
• Phenformix
• Retardo
• W 32
• β-PEBG
• β-Phenethylbiguanide
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-

Imidodicarbonimidic diamide, N-(2-phenylethyl)-

CAS: 114-86-3

• Formula: C₁₀H₁₅N₅
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 205.2596

N-Phenethylbiguanide

CAS: 114-86-3

• Molecular weight: 205.26g/mol

Phenformin

CAS: 114-86-3

• Purity: 97.07%
• Molecular weight: 205.26g/mol

Phenformin

CAS: 114-86-3

Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.

• Formula: C₁₀H₁₅N₅
• Purity: 97.07%
• Color and Shape: Solid
• Molecular weight: 205.26

Phenformin

CAS: 114-86-3

Phenformin is a drug that belongs to the group of biguanides. It inhibits the activity …

• Formula: C₁₀H₁₅N₅
• Purity: Min. 95%
• Molecular weight: 205.26 g/mol