CAS 114-86-3

Phenformin

Description:

Phenformin is a biguanide derivative, primarily recognized for its role as an antihyperglycemic agent in the management of type 2 diabetes mellitus. It is characterized by its ability to decrease hepatic glucose production and enhance insulin sensitivity, thereby improving glucose uptake in peripheral tissues. Phenformin is known for its lipophilic nature, which allows it to penetrate cell membranes effectively. The compound has a relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. It is also associated with a risk of lactic acidosis, a serious side effect that has led to its withdrawal from the market in many countries. In terms of chemical structure, Phenformin features a biguanide backbone, which is essential for its biological activity. Its molecular formula reflects its composition of carbon, hydrogen, nitrogen, and oxygen atoms. Overall, while Phenformin has demonstrated efficacy in glycemic control, its safety profile has limited its clinical use in favor of other antidiabetic medications.

Formula: C₁₀H₁₅N₅

InChI: InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15)

InChI key: InChIKey=ICFJFFQQTFMIBG-UHFFFAOYSA-N

SMILES: C(CNC(NC(=N)N)=N)C1=CC=CC=C1

Synonyms:

• (Phenylethyl)biguanide
• 1-(Diaminomethylidene)-2-(2-phenylethyl)guanidine
• 1-Carbamimidamido-N-(2-phenylethyl)methanimidamide
• 1-Phenethylbiguanide
• Biguanide, 1-phenethyl-
• Cronoformin
• DB Comb.
• DB-retard
• DBI
• Debeone
• Diabis
• Dibiraf
• Dibotin
• Fenfoduron
• Fenformin
• Fenformina
• Fenormin
• Glukopostin
• Glyphen
• N-(2-Phenylethyl)imidodicarbonimidic diamide
• N-(β-Phenethyl)diguanide
• N-(β-phenethyl) biguanide
• Pedg
• Phenethylbiguanide
• Phenformin
• Phenformine
• Phenformix
• Retardo
• W 32
• β-PEBG
• β-Phenethylbiguanide

Phenformin

CAS: 114-86-3

Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.

Formula: C₁₀H₁₅N₅

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 205.26

Ref: TM-T20158

Imidodicarbonimidic diamide, N-(2-phenylethyl)-

CAS: 114-86-3

Formula: C₁₀H₁₅N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 205.2596

Ref: IN-DA000AA2

N-Phenethylbiguanide

CAS: 114-86-3

N-Phenethylbiguanide

Purity: 95%

Molecular weight: 205.26g/mol

Ref: 54-OR471153

Phenformin

CAS: 114-86-3

Phenformin

Purity: ≥95%

Molecular weight: 205.26g/mol

Ref: 54-BUP14095

1-[(diaminomethylidene)amino]-N-(2-phenylethyl)methanimidamide

CAS: 114-86-3

Purity: ≥95%

Molecular weight: 205.2649994

Ref: 10-F830530