CAS 1143-38-0: Dithranol

Description: Dithranol, also known as anthralin, is an organic compound primarily used in dermatological applications, particularly for the treatment of psoriasis. It appears as a yellow to brown crystalline solid and is known for its anti-inflammatory and keratolytic properties. Dithranol functions by inhibiting the proliferation of skin cells and promoting the normalization of skin differentiation, which is beneficial in managing psoriatic lesions. The compound is typically applied topically and can be formulated in various concentrations, depending on the severity of the condition being treated. It is important to note that dithranol can cause skin irritation and staining, necessitating careful application and handling. Additionally, it is sensitive to light and air, which can affect its stability and efficacy. As a chemical substance, dithranol has a relatively low solubility in water but is soluble in organic solvents, making it suitable for incorporation into various topical formulations. Overall, dithranol remains a valuable therapeutic agent in dermatology, particularly for chronic skin conditions.

Formula: C₁₄H₁₀O₃

InChI: InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2

InChI key: InChIKey=NUZWLKWWNNJHPT-UHFFFAOYSA-N

SMILES: O=C1C=2C(O)=CC=CC2CC=3C=CC=C(O)C13

Synonyms:

• 1,8-Dihydroxy-10H-anthracen-9-one
• 1,8-Dihydroxy-9,10-dihydroanthracen-9-one
• 1,8-Dihydroxy-9-Anthrone
• 1,8-Dihydroxy-Anthrone
• 1,8-Dihydroxyanthracen-9(10H)-on
• 1,8-Dihydroxyanthrone
• 1,8-dihidroxiantracen-9(10H)-ona
• 1,8-dihydroxy-9(10H)-anthracenone
• 1,8-dihydroxyanthracen-9(10H)-one
• 1,8-dihydroxyanthracene-9(10H)-one
• 9(10H)-Anthracenone, 1,8-dihydroxy-
• Anthra-Derm
• Anthracene-1,8,9-Triol
• Anthralin
• Anthrone, 1,8-dihydroxy-
• Batidrol
• Batridol
• Batridrol
• Chrysodermol
• Cignolin
• Cigthranol
• Cygnolin
• Dermaline
• Derobin
• DithraSal
• Dithrocream
• DrithoCreme
• Drithoscalp
• Lasan
• Nsc 43970
• Nsc 629313
• Psodadrate
• Psoriacid-Stift
• Psoriacide
• Psorin

Dithranol

CAS: 1143-38-0480-22-8

• Formula: C₁₄H₁₀O₃
• Purity: >95.0%(T)(HPLC)
• Color and Shape: Light yellow to Brown powder to crystal
• Molecular weight: 226.23

1,8,9-Trihydroxyanthracene, 97%

CAS: 1143-38-0

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₄H₁₀O₃
• Purity: 97%
• Color and Shape: Yellow to red, Crystalline powder
• Molecular weight: 226.23

Dithranol

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Purity: 98.8%
• Color and Shape: Yellow-Red Powder
• Molecular weight: 226.06299

Dithranol CRS

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Color and Shape: Crystalline Powder. Yellow. Dark. Powder.
• Molecular weight: 226.2274

Dithranol

CAS: 1143-38-0

Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used …

• Formula: C₁₄H₁₀O₃
• Purity: 93.49% - ≥98%
• Color and Shape: Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder Melting
• Molecular weight: 226.23

9(10H)-Anthracenone, 1,8-dihydroxy-

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 226.2274

Dithranol

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Purity: (Titration) 96.0 - 103.0 % (dried basis)
• Color and Shape: Yellow to orange-brown crystalline powder
• Molecular weight: 226.23

Dithranol, EP grade

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Purity: ≤ 2.5%
• Color and Shape: Yellow or brown-yellow crystalline powder
• Molecular weight: 226.23

1,8-Dihydroxyanthracen-9(10H)-One

CAS: 1143-38-0

• Purity: 98%
• Molecular weight: 226.23g/mol

Dithranol

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Color and Shape: Neat
• Molecular weight: 226.23

Dithranol

CAS: 1143-38-0

• Formula: C₁₄H₁₀O₃
• Color and Shape: Neat
• Molecular weight: 226.23

Anthralin

CAS: 1143-38-0

Stability Hygroscopic Applications Antipsoriatic. References Ashton, R.E., et al.: J. Am. Acad. Dermatol., 9, 173 …

• Formula: C₁₄H₁₀O₃
• Color and Shape: Yellow-Orange
• Molecular weight: 226.23

Anthralin

CAS: 1143-38-0

Anthralin is a synthetic retinoid that has been used to treat bowel diseases such as …

• Formula: C₁₄H₁₀O₃
• Purity: Min. 95 Area-%
• Color and Shape: Yellow Powder
• Molecular weight: 226.23 g/mol

Anthralin

CAS: 1143-38-0

Ketone-phenols and ketones with other oxygen function

• Formula: C₁₄H₁₀O₃
• Color and Shape: Yellow Brownish Yellow Microcrystalline Powder
• Molecular weight: 226.06299