CAS 114522-16-6

1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-

CAS: 114522-16-6

Formula: C₈H₁₄N₄O₄

Color and Shape: Solid

Molecular weight: 230.2212

Ref: IN-DA000EM0

5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)

Controlled Product

CAS: 114522-16-6

Applications 5,6-Dihydro-5-aza-2’-deoxycytidine is a selective mutagen that induces A-to-G and G-to-A mutations in the genome of replicating HIV. First-in-class lethal mutagen of HIV-1; Anti-HIV inhibitor.
References Peng, C. S., et al.: Proc. Natl. Acad. Sci. U.S.A., 112, 3229-3234 (2015); Rawson, J. M., et al.: Bioorg. Med. Chem., 21, 7222-7228 (2013); Murakami, E., et al.: Antiviral Res., 67, 10-17 (2005)

Formula: C₈H₁₄N₄O₄

Color and Shape: Neat

Molecular weight: 230.22

Ref: TR-D447775

5,6-Dihydro-5-aza-2-deoxycytidine

CAS: 114522-16-6

5,6-Dihydro-5-aza-2-deoxycytidine is a purine antimetabolite that inhibits DNA synthesis. The compound binds to the enzyme thymidylate synthase, which converts deoxyuridine monophosphate to thymidylate. It also binds to the receptor for 5,6-dihydro-5-aza-2'-deoxycytidine, which is expressed on cells of the immune system. This binding prevents activation of lymphocytes and inhibits cell proliferation.

Formula: C₈H₁₄N₄O₄

Purity: Min. 95%

Molecular weight: 230.22 g/mol

Ref: 3D-PEA52216

KP-1212

CAS: 114522-16-6

KP-1212( SN-1212) is a nucleoside designed for the treatment of HIV by viral mutagenesis.

Formula: C₈H₁₄N₄O₄

Color and Shape: Solid

Molecular weight: 230.22

Ref: TM-T32418