CAS 114748-67-3

7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine

Description:

7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine is a modified nucleoside that belongs to the class of purine analogs. This compound features a deaza substitution at the 7-position of the guanine base, which alters its hydrogen bonding properties and can influence its biological activity. The presence of the iodine atom at the 7-position enhances its potential for incorporation into nucleic acids, making it of interest in medicinal chemistry and molecular biology. The dideoxy modification at the 2' and 3' positions prevents further phosphorylation, which can affect its role in nucleic acid synthesis and stability. This compound may exhibit unique interactions with enzymes involved in nucleic acid metabolism, potentially serving as a tool in antiviral or anticancer research. Its structural modifications can also impact its solubility, stability, and affinity for nucleic acid targets. Overall, 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine represents a valuable compound for exploring nucleoside analogs and their therapeutic applications.

Formula: C₁₁H₁₃IN₄O₃

Synonyms:

• 7-I-7-Deaza-ddG
• 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
• 7-Iodo-2',3'-Dideoxy-7-Deaza-D-Guanosine
• 7-Iodo-7-Deaza-2',3'-dideoxyguanosine
• 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-
• 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine
• 2-Amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-4H-pyrrolo[2,3-d]pyrimidin-4-one
• 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7-Deaza-2'3'-dideoxy-7-iodoguanosine
• 7-Deaza-7-I-ddG
• 7-Deaza-2',3'-dideoxy-7-iodoguanosine

7-Iodo-7-deaza-dideoxyguanosine

CAS: 114748-67-3

Formula: C₁₁H₁₃IN₄O₃

Purity: 99.17%

Molecular weight: 376.1504

Ref: IN-DA000F5O

7-Iodo-2',3'-dideoxy-7-deaza-guanosine

CAS: 114748-67-3

7-Iodo-2',3'-dideoxy-7-deaza-guanosine

Purity: 98%

Molecular weight: 376.15g/mol

Ref: 54-OR1034315

7-Iodo-2',3'-dideoxy-7-deaza-guanosine

CAS: 114748-67-3

Molecular weight: 376.154

Ref: 10-F986390

7-Iodo-2',3'-dideoxy-7-deaza-guanosine

CAS: 114748-67-3

7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside compound with applications in DNA synthesis and sequencing reactions.

Formula: C₁₁H₁₃IN₄O₃

Color and Shape: Solid

Molecular weight: 376.15

Ref: TM-T38530

7-Deaza-2',3'-dideoxy-7-iodoguanosine

CAS: 114748-67-3

7-Deaza-2',3'-dideoxy-7-iodoguanosine is a nucleoside analog that inhibits the synthesis of DNA by inhibiting the activity of DNA polymerase. It is used to treat HIV and other viral infections. The compound is also active against cancer cells and has been shown to inhibit the growth of leukemia cells. 7-Deaza-2',3'-dideoxy-7-iodoguanosine is modified with an iodine atom at the 7 position and has a novel structure. This compound is used in biological research as a substrate for the preparation of phosphate esters such as phosphoramidites for use in oligonucleotide synthesis.

Formula: C₁₁H₁₃N₄O₃I

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 376.15 g/mol

Ref: 3D-NI57362