CymitQuimica logo

CAS 114748-67-3

:

7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine

Description:
7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine is a modified nucleoside that belongs to the class of purine analogs. This compound features a deaza substitution at the 7-position of the guanine base, which alters its hydrogen bonding properties and can influence its biological activity. The presence of the iodine atom at the 7-position enhances its potential for incorporation into nucleic acids, making it of interest in medicinal chemistry and molecular biology. The dideoxy modification at the 2' and 3' positions prevents further phosphorylation, which can affect its role in nucleic acid synthesis and stability. This compound may exhibit unique interactions with enzymes involved in nucleic acid metabolism, potentially serving as a tool in antiviral or anticancer research. Its structural modifications can also impact its solubility, stability, and affinity for nucleic acid targets. Overall, 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine represents a valuable compound for exploring nucleoside analogs and their therapeutic applications.
Formula:C11H13IN4O3
InChI:InChI=1S/C11H13IN4O3/c12-6-3-16(7-2-1-5(4-17)19-7)9-8(6)10(18)15-11(13)14-9/h3,5,7,17H,1-2,4H2,(H3,13,14,15,18)/t5-,7+/m0/s1
InChI key:KJNOBXXCZQLWLF-CAHLUQPWSA-N
SMILES:C1C[C@@H](O[C@@H]1CO)N2C=C(C3=C2N=C(NC3=O)N)I
Synonyms:
  • 7-I-7-Deaza-ddG
  • 2-Amino-7-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
  • 7-Iodo-2',3'-Dideoxy-7-Deaza-D-Guanosine
  • 7-Iodo-7-Deaza-2',3'-dideoxyguanosine
  • 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-
  • 7-Iodo-2',3'-Dideoxy-7-Deaza-Guanosine
  • 2-Amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-4H-pyrrolo[2,3-d]pyrimidin-4-one
  • 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-iodo-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7-Deaza-2'3'-dideoxy-7-iodoguanosine
  • 7-Deaza-7-I-ddG
  • 7-Deaza-2',3'-dideoxy-7-iodoguanosine
Found 6 products.