CAS 114915-17-2

7-Troc-Paclitaxel

Description:

7-Troc-Paclitaxel, with the CAS number 114915-17-2, is a derivative of the well-known chemotherapeutic agent paclitaxel, which is primarily used in the treatment of various cancers, including ovarian and breast cancer. The "Troc" in its name refers to a tert-butyloxycarbonyl (Boc) protecting group, which is often used in organic synthesis to protect functional groups during chemical reactions. This modification can influence the compound's solubility, stability, and biological activity. 7-Troc-Paclitaxel retains the core structure of paclitaxel, which includes a taxane ring system and an ester side chain, contributing to its mechanism of action that involves the stabilization of microtubules and inhibition of cell division. The presence of the Troc group may enhance its pharmacokinetic properties, potentially improving its therapeutic efficacy or reducing toxicity. As with many derivatives, the specific characteristics, such as solubility and reactivity, can vary significantly from the parent compound, making it an important subject of study in medicinal chemistry and drug development.

Formula: C₅₀H₅₂Cl₃NO₁₆

Synonyms:

• (N-1)Paxlitaxl intermediate 2
• 7-Troc-paclitaxel,98%min
• 7-(2,2,2-Trichloroethyloxycarbonyl)taxol
• Hydrocortisone Acetate Impurity 6 (Hydrocortisone Acetate EP Impurity F)
• 7 Troc paclitaxel,7Trocpaclitaxel
• 7-Troc-Paclitaxel
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-...
• Intermediate of paclitaxel
• Paclitaxel Impurity 50

7-Troc-paclitaxel

CAS: 114915-17-2

7-Troc-paclitaxel

Formula: C₅₀H₅₂Cl₃NO₁₆

Purity: ≥98%

Molecular weight: 1029.3

Ref: 54-BUP09745

7-Troc Paclitaxel

CAS: 114915-17-2

Formula: C₅₀H₅₂Cl₃NO₁₆

Molecular weight: 1029.33

Ref: 4Z-P-2839

7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel-d5

Controlled Product

CAS: 114915-17-2

Applications Labelled 7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel is used in the semi-synthesis of Taxol (P132500) and Docetaxel (D494420).
References Commercon, A., et al.: Tetrahedr. Lett., 33, 5185 (1992),

Formula: C₅₀D₅H₄₇Cl₃NO₁₆

Color and Shape: Neat

Molecular weight: 1034.33

Ref: TR-T774147

7-{[(2,2,2,-Trichloroethyl)oxy]carbonyl} Paclitaxel

Controlled Product

CAS: 114915-17-2

Formula: C₅₀H₅₂Cl₃NO₁₆

Color and Shape: Neat

Molecular weight: 1029.304

Ref: TR-T774146

Paclitaxel 7-Troc Paclitaxel

CAS: 114915-17-2

Formula: C₅₀H₅₂Cl₃NO₁₆

Molecular weight: 1029.3

Ref: ST-EA-CP-P36201

7-Troc-paclitaxel

CAS: 114915-17-2

7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity.

Formula: C₅₀H₅₂Cl₃NO₁₆

Purity: 99.69%

Color and Shape: White Solid

Molecular weight: 1029.3

Ref: TM-T20864