CAS 115066-14-3

6-Cyano-7-nitroquinoxaline-2,3-dione

Description:

6-Cyano-7-nitroquinoxaline-2,3-dione, with the CAS number 115066-14-3, is a synthetic organic compound that belongs to the class of quinoxaline derivatives. This compound is characterized by its bicyclic structure, which features a quinoxaline core with a cyano group at the 6-position and a nitro group at the 7-position. It is known for its role as a selective antagonist of certain glutamate receptors, particularly in neuropharmacological research, making it valuable in studying synaptic transmission and neurodegenerative diseases. The presence of both cyano and nitro functional groups contributes to its reactivity and potential applications in medicinal chemistry. Additionally, this compound exhibits properties that allow it to interact with biological systems, influencing various signaling pathways. Its solubility and stability can vary depending on the solvent and conditions, which is important for its use in laboratory settings. Overall, 6-Cyano-7-nitroquinoxaline-2,3-dione is a significant compound in the field of neuroscience and pharmacology.

Formula: C₉H₄N₄O₄

InChI: InChI=1/C9H2N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H

InChI key: InChIKey=RPXVIAFEQBNEAX-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1C=C2C(=CC1C#N)NC(=O)C(=O)N2

Synonyms:

• 1,2,3,4-Tetrahydro-7-nitro-2,3-dioxo-6-quinoxalinecarbonitrile
• 2,3-Dioxo-7-nitro-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile
• 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline
• 6-Cyano-7-Nitroquinoxaline-2,3-Dione 2Na
• 6-Cyano-7-Nitroquinoxaline-2,3-Dione Disodium
• 6-Cyano-7-Nitroquinoxaline-2,3-Dione Disodium Salt
• 6-Quinoxalinecarbonitrile, 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-
• 7-Nitro-2,3-Dioxo-2,3-Dihydroquinoxaline-6-Carbonitrile
• Cnqx
• Cnqx 2Na
• Cnqx Disodium
• Cnqx Disodium Salt
• Disodium 6-Cyano-7-Nitroquinoxaline-2,3-Diolate
• Fg 9065
• 6-Cyano-7-nitroquinoxaline-2,3-dione
• 6-CYANO-7-NITROQUINOXALINE-2,3 (1H,4H)-DIONE
• 6-Cyano-7-nitroquinoxaline-2,3-dione, FG-9065
• CNQX (FG-9065) (6-CYANO-7-NITROQUINO
• 2,3-Dioxo-7-nitroquinoxaline-6-carbonitrile
• 6-Nitro-7-cyanoquinoxaline-2,3-dione
• 7-Nitro-2,3-dihydroxyquinoxaline-6-carbonitrile
• CNOX

CNQX

CAS: 115066-14-3

Formula: C₉H₄N₄O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 232.16

Ref: 3B-C3725

6-QUINOXALINECARBONITRILE, 1,2,3,4-TETRAHYDRO-7-NITRO-2,3-DIOXO-

CAS: 115066-14-3

Formula: C₉H₄N₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.1525

Ref: IN-DA000FV3

6-Cyano-7-nitroquinoxaline-2,3-dione

CAS: 115066-14-3

6-Cyano-7-nitroquinoxaline-2,3-dione

Purity: 97%

Molecular weight: 232.15g/mol

Ref: 54-OR9820T

6-Cyano-7-nitroquinoxaline-2,3 (1H,4H)-dione

CAS: 115066-14-3

Formula: C₉H₄N₄O₄

Molecular weight: 232.16

Ref: 7W-GK8604

CNQX

CAS: 115066-14-3

CNQX

Purity: ≥95%

Molecular weight: 232.15g/mol

Ref: 54-BUP10584

CNQX

CAS: 115066-14-3

CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)

Formula: C₉H₄N₄O₄

Purity: 99.70%

Color and Shape: Pale Yellow Solid

Molecular weight: 232.15

Ref: TM-T7178

6-Cyano-7-nitroquinoxaline-2,3-dione

Controlled Product

CAS: 115066-14-3

Stability Store Tightly Sealed at RT
Applications A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively.
References Honore, et al. Science, 241, 701 (1988),Haas, H.S., et al.: Int. J. Oncol., 27, 867 (2005), Kobayashi, K., et al.: J. Pharmacol. Sci., 108, 517 (2008), Shabat-Simon, M., et al.: J. Neurosci., 28, 8406 (2008), Cruz, L.A., et al.: J. Med. Chem., 51, 5856 (2008),

Formula: C₉H₄N₄O₄

Color and Shape: Neat

Molecular weight: 232.15

Ref: TR-C982000

CNQX

CAS: 115066-14-3

Purity: 98%

Molecular weight: 232.023

Ref: 10-F828417

CNQX

CAS: 115066-14-3

Glutamate antagonist

Formula: C₉H₄N₄O₄

Purity: Min. 95%

Molecular weight: 232.15 g/mol

Ref: 3D-FC20628

6-Cyano-7-nitro-1,4-dihydroquinoxaline-2,3-dione, 98%

CAS: 115066-14-3

Potent, selective kainate/quisqualate (non-NMDA) receptor antagonist

Formula: C₉H₄N₄O₄

Purity: 98%

Molecular weight: 232.16

Ref: 02-J63472