CAS 1152311-62-0: 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide

Description: The chemical substance known as "1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide," with the CAS number 1152311-62-0, is a complex organic compound characterized by its unique structural features, including a cyclopropanecarboxamide moiety and multiple fluorinated and hydroxylated groups. This compound is likely to exhibit significant biological activity due to its intricate arrangement of functional groups, which may influence its interactions with biological targets. The presence of fluorine atoms typically enhances lipophilicity and metabolic stability, while hydroxyl groups can increase solubility and hydrogen bonding potential. The benzodioxole and indole components suggest potential applications in medicinal chemistry, possibly as a pharmaceutical agent. Its synthesis and characterization would involve advanced organic chemistry techniques, and its properties, such as solubility, stability, and reactivity, would be critical for understanding its potential applications in drug development or other fields. Further studies would be necessary to elucidate its specific biological activities and mechanisms of action.

Formula: C₂₆H₂₇F₃N₂O₆

InChI: InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1

InChI key: InChIKey=MJUVRTYWUMPBTR-MRXNPFEDSA-N

SMILES: O=C(NC1=CC=2C=C(N(C2C=C1F)CC(O)CO)C(C)(C)CO)C3(C4=CC=C5OC(F)(F)OC5=C4)CC3

Synonyms:

• (R)-1-(2,2-Difluorobenzo[D] [1,3]Dioxol-5-Yl)-N-(1-(2,3-Dihydroxypropyl)-6-Fluoro-2-(1-Hydroxy-2-Methylpropan-2-Yl)-1H-Indol-5-Yl) Cyclopropanecarboxamide
• 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide
• 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-{1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methyl-2-propanyl)-1H-indol-5-yl}cyclopropanecarboxamide
• Cs-1078
• Cyclopropanecarboxamide, 1-(2,2-Difluoro-1,3-Benzodioxol-5-Yl)-N-[1-[(2R)-2,3-Dihydroxypropyl]-6-Fluoro-2-(2-Hydroxy-1,1-Dimethylethyl)-1H-Indol-5-Yl]-
• Tezacaftor
• VX 661

Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-

CAS: 1152311-62-0

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 520.4976

Tezacaftor (VX-661)

CAS: 1152311-62-0

• Formula: C₂₆H₂₇F₃N₂O₆
• Molecular weight: 520.51

Tezacaftor

CAS: 1152311-62-0

• Color and Shape: Neat

Tezacaftor

CAS: 1152311-62-0

Tezacaftor (VX661) is a small molecule that can be used as a corrector of the …

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: 100% - 99.69%
• Color and Shape: Solid
• Molecular weight: 520.5

Tezacaftor

CAS: 1152311-62-0

Applications Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients …

• Formula: C₂₆H₂₇F₃N₂O₆
• Color and Shape: White To Light Yellow
• Molecular weight: 520.5

Tezacaftor-D4

CAS: 1152311-62-0

• Formula: C₂₆D₄H₂₃F₃N₂O₆
• Color and Shape: Neat
• Molecular weight: 524.52

Tezacaftor

CAS: 1152311-62-0

Potentiates cystic fibrosis transmembrane conductance regulator (CFTR)

• Formula: C₂₆H₂₇F₃N₂O₆
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 520.5 g/mol