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CAS 115436-72-1

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Risedronate sodium

Description:
Risedronate sodium is a bisphosphonate medication primarily used to treat osteoporosis and other conditions that result in bone loss. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density and reducing the risk of fractures. The compound is characterized by its ability to bind to hydroxyapatite in bone, which enhances its therapeutic efficacy. Risedronate sodium is typically administered orally and is known for its relatively good bioavailability compared to other bisphosphonates. It is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure, which includes a pyridinyl group. The compound is generally well-tolerated, although it may cause gastrointestinal side effects in some patients. Additionally, it is important for patients to remain upright for a period after taking the medication to minimize esophageal irritation. Overall, Risedronate sodium plays a significant role in the management of bone health, particularly in postmenopausal women and individuals at risk for osteoporosis.
Formula:C7H11NO7P2·Na
InChI:InChI=1S/C7H11NO7P2.Na/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);
InChI key:InChIKey=JAROYDNJQWMRAM-UHFFFAOYSA-N
SMILES:C(CC=1C=CC=NC1)(P(=O)(O)O)(P(=O)(O)O)O.[Na]
Synonyms:
  • 3-Pyridyl-1-hydroxyethylidene-1,1-biphosphonic acid sodium salt
  • Actonel
  • Atelvia
  • Fossical
  • Gemfos
  • Ne 58095
  • Phosphonic Acid, [1-Hydroxy-2-(3-Pyridinyl)Ethylidene]Bis-, Monosodium Salt
  • Phosphonic acid, P,P′-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-, sodium salt (1:1)
  • Risedronate sodium
  • Risedronic acid monosodium salt
  • See more synonyms
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