CAS 1155-62-0

N-Benzyloxycarbonyl-L-glutamic acid

Description:

N-Benzyloxycarbonyl-L-glutamic acid, commonly referred to as Z-L-glutamic acid, is a derivative of the amino acid glutamic acid, characterized by the presence of a benzyloxycarbonyl (Z) protecting group. This compound is typically utilized in peptide synthesis as a protecting group for the amino group of glutamic acid, facilitating the selective modification of other functional groups during chemical reactions. It is a white to off-white crystalline solid that is soluble in organic solvents such as methanol and dimethyl sulfoxide, but less soluble in water. The presence of the benzyloxycarbonyl group enhances the stability of the amino acid under various reaction conditions, making it a valuable intermediate in the synthesis of peptides and other bioactive compounds. Additionally, N-Benzyloxycarbonyl-L-glutamic acid can participate in various chemical reactions, including coupling reactions with other amino acids, contributing to its utility in organic synthesis and medicinal chemistry. Its molecular structure includes both carboxylic acid and amine functional groups, which are crucial for its reactivity and interactions in biochemical processes.

Formula: C₁₃H₁₅NO₆

InChI: InChI=1/C13H15NO6/c15-11(16)7-6-10(12(17)18)14-13(19)20-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,19)(H,15,16)(H,17,18)/t10-/m1/s1

InChI key: InChIKey=PVFCXMDXBIEMQG-JTQLQIEISA-N

SMILES: C(OC(N[C@@H](CCC(O)=O)C(O)=O)=O)C1=CC=CC=C1

Synonyms:

• (2S)-2-(Phenylmethoxycarbonylamino)pentanedioic acid
• (2S)-2-[[(Benzyloxy)carbonyl]amino]pentanedioic acid
• (S)-2-(((Benzyloxy)carbonyl)amino)pentanedioic acid
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[(phenylmethoxy)carbonyl]-
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutamic acid
• Carbobenzoxy-<span class="text-smallcaps">L</span>-glutamic acid
• Cbz-Glu-OH
• Cbz-L-glutamic acid
• Glutamic acid, N-carboxy-, N-benzyl ester
• Glutamic acid, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutamic acid
• N-(Benzyloxycarbonyl)glutamic acid
• N-(Carbobenzyloxy)-L-glutamic acid
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-glutamic acid
• N-Carbobenzoxy-L-glutamic acid
• N-Cbz-<span class="text-smallcaps">L</span>-glutamic acid
• N-Cbz-L-glutamic acid
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-[(benzyloxy)carbonyl]-D-glutamic acid
• N-[(benzyloxy)carbonyl]glutamic acid
• NSC 555
• NSC 88494
• Z-Glu-OH
• Z-L-Glutamic acid
• z-Glu
• Glutamic acid, N-carboxy-, N-benzyl ester, L-
• L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-
• N-[(Phenylmethoxy)carbonyl]-L-glutamic acid
• N-ALPHA-BENZYLOXYCARBONYL-L-GLUTAMIC-ACID
• n-[(phenylmethoxy)carbonyl]-l-glutamicaci
• CARBOBENZOXY-L-GLUTAMIC ACID
• Z-GLUTAMIC ACID
• (S)-2-BENZYLOXYCARBONYLAMINO-PENTANEDIOIC ACID
• NA-CBZ-L-GLUTAMIC ACID
• N-CBZ-L-GLUTAMIC ACID-OH
• Z-L-GLU-OH
• N-ALPHA-CARBOBENZOXY-L-GLUTAMIC ACID
• N-BENZYLOXYCARBONYL-L-GLUTAMIC ACID
• N-ALPHA-CBZ-L-GLUTAMIC ACID

N-Benzyloxycarbonyl-L-glutamic Acid

CAS: 1155-62-0

Formula: C₁₃H₁₅NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White powder to crystal

Molecular weight: 281.26

Ref: 3B-C0734

N-Benzyloxycarbonyl-L-glutamic acid, 99%

CAS: 1155-62-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₃H₁₅NO₆

Purity: 99%

Color and Shape: Powder, White

Molecular weight: 281.26

Ref: 02-A17686

Z-Glu-OH

CAS: 1155-62-0

Bachem ID: 4000114.

Formula: C₁₃H₁₅NO₆

Purity: 99.2%

Color and Shape: White

Molecular weight: 281.27

Ref: 01-4000114

L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-

CAS: 1155-62-0

Formula: C₁₃H₁₅NO₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 281.2613

Ref: IN-DA000G3D

Z-Glu-OH

CAS: 1155-62-0

Formula: C₁₃H₁₅NO₆

Molecular weight: 281.27

Ref: 7W-GM1213

N-Benzyloxycarbonyl-L-glutamic acid

CAS: 1155-62-0

N-Benzyloxycarbonyl-L-glutamic acid

Purity: 98%

Molecular weight: 281.26g/mol

Ref: 54-OR1014278

Z-Glu-OH

CAS: 1155-62-0

M03047 - Z-Glu-OH

Formula: C₁₃H₁₅NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.264

Ref: 10-M03047

N-Carbobenzyloxy-L-glutamic Acid

Controlled Product

CAS: 1155-62-0

Applications Used for the synthesis of carboxyalkyl peptides as inhibitors of angiotensin-converting enzyme of human blood serum.
References Anderson, A., et al.: Chem. Biol., 8, 445 (2001), Claussen, H., et al.: J. Mol. Biol., 308, 377 (2001), Sherman, W., et al.: J. Med. Chem., 49, 534 (2006),

Formula: C₁₃H₁₅NO₆

Color and Shape: Neat

Molecular weight: 281.26

Ref: TR-C176510

Z-L-Glutamic Acid extrapure, 99%

CAS: 1155-62-0

Formula: C₁₃H₁₅NO₆

Purity: min. 99 %

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 281.27

Ref: SR-67271